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Palladium-catalyzed ligand-free and efficient Suzuki-Miyaura reaction of heteroaryl halides with MIDA boronates in water

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Indexed by:期刊论文

Date of Publication:2015-01-01

Journal:RSC ADVANCES

Included Journals:SCIE、EI、Scopus

Volume:5

Issue:67

Page Number:54312-54315

ISSN No.:2046-2069

Abstract:A simple and environment-friendly protocol for the palladium-catalyzed ligand-free Suzuki-Miyaura reaction of heteroaryl halides with N-methyliminodiacetic acid (MIDA) boronates is developed. The reaction is performed in water as the sole medium and allows the preparation of a variety of heterobiaryls in excellent yields.

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