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Palladium-catalyzed efficient Suzuki-Miyaura reaction of potassium aryltrifluoroborates in water

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Indexed by:Journal Papers

Date of Publication:2015-09-05

Journal:CATALYSIS COMMUNICATIONS

Included Journals:SCIE、EI

Volume:69

Issue:1

Page Number:81-85

ISSN No.:1566-7367

Key Words:Palladium; Suzuld-Miyaura reaction; Alyltrifluoroborates; Water; Gram scale

Abstract:An efficient and environment-friendly protocol has been developed for the palladium-catalyzed Suzuki-Miyaura reaction of potassium aryltrifluoroborates with (hetero)aryl halides in water without any additive. This method allows the preparation of a variety of biaryls and heterobiaryls in excellent yields. In addition, the cross-coupling product can be isolated in good yields and high purity by simple filtration and recrystallization as the reaction was performed on gram scale. (C) 2015 Elsevier B.V. All rights reserved.

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