Release Time:2019-03-11  Hits:

Indexed by: Journal Article

Date of Publication: 2018-05-16

Journal: CHEMICAL PHYSICS LETTERS

Included Journals: EI、SCIE

Volume: 700

Page Number: 80-87

ISSN: 0009-2614

Key Words: Initial saturation; Drying time; Adsorption; Sublimation-desorption; Mass transfer

Abstract: Freeze-drying of initially porous frozen material was investigated aimed at improving the process economics by reducing drying time and raising productivity. Experimental results showed that freeze-drying can be significantly enhanced by the frozen material with prebuilt porosity, and about 31% of drying time can be saved compared with the conventionally solid frozen material under the tested operating conditions. A multiphase transport model was formulated based on the local mass non-equilibrium assumption. Numerical results showed excellent agreements between measured and predicted drying curves. Analyses of saturation and temperature profiles displayed that volumetric sublimation-desorption can occur for the initially porous frozen material. (C) 2018 Elsevier B.V. All rights reserved.