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Indexed by:期刊论文

Date of Publication:2018-05-16

Journal:CHEMICAL PHYSICS LETTERS

Included Journals:SCIE、EI

Volume:700

Page Number:80-87

ISSN No.:0009-2614

Key Words:Initial saturation; Drying time; Adsorption; Sublimation-desorption; Mass transfer

Abstract:Freeze-drying of initially porous frozen material was investigated aimed at improving the process economics by reducing drying time and raising productivity. Experimental results showed that freeze-drying can be significantly enhanced by the frozen material with prebuilt porosity, and about 31% of drying time can be saved compared with the conventionally solid frozen material under the tested operating conditions. A multiphase transport model was formulated based on the local mass non-equilibrium assumption. Numerical results showed excellent agreements between measured and predicted drying curves. Analyses of saturation and temperature profiles displayed that volumetric sublimation-desorption can occur for the initially porous frozen material. (C) 2018 Elsevier B.V. All rights reserved.