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个人信息Personal Information
副教授
硕士生导师
性别：女
毕业院校：大连理工大学
学位：博士
所在单位：医学部
学科：有机化学. 细胞生物学
办公地点：大连理工大学西部新校区化学综合楼C508
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- [1]宋婷.张志超,王沛然,于晓燕,王安辉,柴高波,范玉丹.Systems analysis of phosphorylationregulated Bcl-2 interactions establishes a model to reconcile the controversy over the[J],British Journal of Pharmacology,2018,176:491-504
- [2]Song, Ting.Zhang, ZC (reprint author), Dalian Univ Technol, Sch Chem, Dalian, Liaoning, Peoples R China..Chai, Gaobo,Li, Xiangqian,Li, Zhiqiang,Zhang, Zhichao,Wang, Ziqian,Ji, Fangling,Feng, Yingang,Fan, Yudan.Deactivation of Mcl-1 by Dual-Function Small-Molecule Inhibitors Targeting the Bcl-2 Homology 3 Domain and Facilitating Mcl-1 Ubiquitination[J],ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2016,55(46):14248-14254
- [3]Song, Ting.Zhang, Z (reprint author), Dalian Univ Technol, Sch Chem, State Key Lab Fine Chem, 2 Ling Gong Rd, Dalian, Peoples R China..Wang, Ziqian,Zhang, Zhichao.Substituted indole Mcl-1 inhibitors: a patent evaluation (WO2015148854A1)[J],EXPERT OPINION ON THERAPEUTIC PATENTS,2016,26(11):1227-1238
- [4]Wang, Anhui.Zhang, ZC (reprint author), Dalian Univ Technol, Sch Chem, State Key Lab Fine Chem, Dalian 116024, Peoples R China..Song, Ting,Wang, Ziqian,Liu, Yubo,Fan, Yudan,Zhang, Yahui,Zhang, Zhichao.Mechanism of Mcl-1 Conformational Regulation Upon Small Molecule Binding Revealed by Molecular Dynamic Simulation[J],CHEMICAL BIOLOGY & DRUG DESIGN,2016,87(4):551-561
- [5]Song, Ting.Zhang, ZC (reprint author), Dalian Univ Technol, Sch Chem, State Key Lab Fine Chem, Dalian 116024, Peoples R China..Wang, Ziqian,Zhang, Zhichao,Chai, Gaobo,Liu, Yubo,Yu, Xiaoyan.Bcl-2 phosphorylation confers resistance on chronic lymphocytic leukaemia cells to the BH3 mimetics ABT-737, ABT-263 and ABT-199 by impeding direct binding[J],BRITISH JOURNAL OF PHARMACOLOGY,2016,173(3):471-483
- [6]宋婷.张志超.Bcl-2/MDM2 Dual Inhibitors Based On Universal Pyramid-Like alpha-Helical Mimetics[A],2016,59(7):3152-3162
- [7]Song, Ting.Zhang, ZC (reprint author), Dalian Univ Technol, Sch Chem, State Key Lab Fine Chem, Dalian, Peoples R China..Zhang, Zhichao,Chai, Gaobo,Liu, Yubo,Xie, Mingzhou,Chen, Qingbin,Yu, Xiaoyan,Sheng, Hongkun.Mechanism of synergy of BH3 mimetics and paclitaxel in chronic myeloid leukemia cells: Mcl-1 inhibition[J],EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,2015,70:64-71
- [8]Song, Ting.Zhang, ZC (reprint author), Dalian Univ Technol, State Key Lab Fine Chem, Sch Chem, Dalian 116024, Peoples R China..Chai, Gaobo,Yu, Xiaoyan,Liu, Yubo.Discovery of a Small-Molecule pBcl-2 Inhibitor that Overcomes pBcl-2-Mediated Resistance to Apoptosis[J],CHEMBIOCHEM,2015,16(5):757-765
- [9]Liu, Yubo.Zhang, ZC (reprint author), Dalian Univ Technol, Sch Chem, State Key Lab Fine Chem, Dalian, Peoples R China..Song, Ting,Sheng, Hongkun,Yu, Xiaoyan,Zhang, Zhichao,Xie, Mingzhou.A novel BH3 mimetic efficiently induces apoptosis in melanoma cells through direct binding to anti-apoptotic Bcl-2 family proteins, including phosphorylated Mcl-1[J],PIGMENT CELL & MELANOMA RESEARCH,2015,28(2):161-170
- [10]Song, Ting.Feng, YG (reprint author), Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, Qingdao 266101, Peoples R China..Zhang, Zhichao,Su, Pengchen,Feng, Yingang,Wu, Guiye,Xie, Shenghui,Li, Xiangqian,Yang, Ying.3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-x(L) and Mcl-1 (vol 21, pg 11, 2013)[J],BIOORGANIC & MEDICINAL CHEMISTRY,2014,22(1):663-664