徐琴琴   

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Supervisor of Master's Candidates

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Language:English

Paper Publications

Title of Paper:应用超临界流体技术制备药物微粒

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Date of Publication:2011-10-10

Journal:化工装备技术

Volume:32

Issue:5

Page Number:38-45

ISSN No.:1007-7251

Key Words:超临界流体;药物微粒;溶液;浸渍;抗溶剂;饱和溶液

Abstract:超临界流体技术在药物制备中的应用,尤其在药物微粒化方面的应用成效显著.分析了超临界流体技术在国内外的研究进展,并进行归纳总结.其内容包括:超临界流体溶液快速膨胀、超临界流体浸渍、超临界流体抗溶剂以及超临界流体过饱和溶液等技术.着重就实际应用中所关心的实验原理、工艺流程、容器设备等内容进行分析对比,以此讨论其优缺点.此外,还就深入研发过程中应该注意解决的关键问题及其应用前景提出了初步建议.

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