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A Metal-Organic Framework/DNA Hybrid System as a Novel Fluorescent Biosensor for Mercury(II) Ion Detection

Release Time:2019-03-13  Hits:

Indexed by: Journal Article

Date of Publication: 2016-01-11

Journal: CHEMISTRY-A EUROPEAN JOURNAL

Included Journals: PubMed、EI、SCIE

Volume: 22

Issue: 2

Page Number: 477-480

ISSN: 0947-6539

Key Words: DNA; fluorescence; host-guest systems; mercury; metal-organic frameworks

Abstract: Mercury(II) ions have emerged as a widespread environmental hazard in recent decades. Despite different kinds of detection methods reported to sense Hg2+, it still remains a challenging task to develop new sensing molecules to replenish the fluorescence-based apparatus for Hg2+ detection. This communication demonstrates a novel fluorescent sensor using UiO-66-NH2 and a T-rich FAM-labeled ssDNA as a hybrid system to detect Hg2+ sensitively and selectively. To the best of our knowledge, it has rarely been reported that a MOF is utilized as the bio-sensing platform for Hg2+ assay.

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