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个人信息Personal Information
研究员
博士生导师
硕士生导师
性别：男
毕业院校：德国马普高分子所
学位：博士
所在单位：化工学院
办公地点：大连理工大学西部校区E-226
联系方式：sunwen@dlut.edu.cn
电子邮箱：sunwen@dlut.edu.cn
Gold nanoparticle-based plasmonic probe for selective recognition of adenosine
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论文类型：期刊论文
发表时间：2019-10-01
发表刊物：SENSORS AND ACTUATORS B-CHEMICAL
收录刊物：SCIE、EI
卷号：296
ISSN号：0925-4005
关键字：Plasmonic probe; Adenosine detection; Gold nanoparticle; Eyedropper function; Colorimetric assay
摘要：Adenosine, as an endogenous molecule in organisms, plays an essential role in biological processes. Here, a plasmonic probe, creatinine-Ag+/gold nanoparticle (AuNPs), is assembled for adenosine detection based on synergistic coordination on AuNPs. The A(650 nm/520 nm) values of AuNPs system change linearly with adenosine concentration over a range of 1.0-5.0 mu M and the detection limits reached 45 nM. The adenosine detection is realized within 4 min. Furthermore, the quantitative detection of adenosine is realized by eyedropper (a function in Microsoft's PowerPoint) for analyzing RGB value changes of colorimetric assay. Therefore, this sensor can provide accurate and rapid assay of adenosine in patients' serum sample without complicated instrumentations.
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