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个人信息Personal Information
研究员
博士生导师
硕士生导师
性别：男
毕业院校：德国马普高分子所
学位：博士
所在单位：化工学院
办公地点：大连理工大学西部校区E-226
联系方式：sunwen@dlut.edu.cn
电子邮箱：sunwen@dlut.edu.cn
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A fluorescent probe for site I binding and sensitive discrimination of HSA from BSA
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论文类型：期刊论文
发表时间：2014-08-28
发表刊物：CHEMICAL COMMUNICATIONS
收录刊物：SCIE、PubMed、Scopus
卷号：50
期号：67
页面范围：9573-9576
ISSN号：1359-7345
摘要：A fluorescent probe DH1 has been successfully developed to detect HSA via site I non-covalent bonding. DH1 shows a dramatic fluorescence enhancement towards HSA without interference from other proteins. The molecular docking method, for the first time, was utilized to provide deep insight into the sensing mechanism of the probe. Moreover, probe DH1 was successfully used to detect trace HSA in healthy human urine.