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个人信息Personal Information
研究员
博士生导师
硕士生导师
性别：男
毕业院校：德国马普高分子所
学位：博士
所在单位：化工学院
办公地点：大连理工大学西部校区E-226
联系方式：sunwen@dlut.edu.cn
电子邮箱：sunwen@dlut.edu.cn
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A Ratiometric Near-Infrared Fluorescent Probe for Hydrazine and Its in Vivo Applications
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论文类型：期刊论文
发表时间：2013-08-02
发表刊物：ORGANIC LETTERS
收录刊物：SCIE、PubMed、Scopus
卷号：15
期号：15
页面范围：4022-4025
ISSN号：1523-7060
摘要：Based on modulation of the conjugated polymethine pi-electron system of a cyanine dye derivative, a ratiometric near-infared fluorescent probe (Cy7A) for hydrazine (N2H4) has been designed and synthesized. Cy7A can be selectively hydrazinolysized with great changes in its fluorescent excitation/emission profiles, which makes it possible to detect N2H4 in water samples and living cells and, for the first time, visualize N2H4 in living mice.