个人信息Personal Information
研究员
博士生导师
硕士生导师
性别:男
毕业院校:德国马普高分子所
学位:博士
所在单位:化工学院
办公地点:大连理工大学西部校区E-226
联系方式:sunwen@dlut.edu.cn
电子邮箱:sunwen@dlut.edu.cn
Construction of Long-Wavelength Fluorescein Analogues and Their Application as Fluorescent Probes
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论文类型:期刊论文
发表时间:2013-05-01
发表刊物:CHEMISTRY-A EUROPEAN JOURNAL
收录刊物:SCIE、EI、PubMed、Scopus
卷号:19
期号:21
页面范围:6538-6545
ISSN号:0947-6539
关键字:colorimetric analysis; fluorescence; fluorescent probes; mitochondria; thiol probes; imaging
摘要:Born to dye: Five fluorescein analogues were synthesised (see scheme). One analogue was found to emit in the NIR region with a high quantum yield, excellent photostability and good permeability. Three derivatives were found to specifically stain mitochondria and one dye responds to thiols with a strong turn-on NIR fluorescence signal and colorimetric change, in vitro and in vivo.Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.