Indexed by:Journal Article

Date of Publication:2010-01-01

Journal:CHEMICAL SOCIETY REVIEWS

Included Journals:ESI高被引论文、SCIE

Volume:39

Issue:6

Page Number:2120-2135

ISSN:0306-0012

Abstract:Due to the biological importances of thiols, such as cysteine, homocysteine and glutathione, the development of optical probes for thiols has been an active research area in recent few years. This critical review focuses on the fluorescent or colorimetric sensors for thiols according to their unique mechanisms between sensors and thiols, including Michael addition, cyclization with aldehyde, cleavage of sulfonamide and sulfonate ester by thiols, cleavage of selenium-nitrogen bond by thiols, cleavage of disulfide by thiols, metal complexes-oxidation-reduction, metal complexes-displace coordination, nano-particles and others.