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Palladium-catalyzed ligand-free and efficient Suzuki-Miyaura reaction of heteroaryl halides with MIDA boronates in water

Release Time:2019-03-11  Hits:

Indexed by: Journal Article

Date of Publication: 2015-01-01

Journal: RSC ADVANCES

Included Journals: Scopus、EI、SCIE

Volume: 5

Issue: 67

Page Number: 54312-54315

ISSN: 2046-2069

Abstract: A simple and environment-friendly protocol for the palladium-catalyzed ligand-free Suzuki-Miyaura reaction of heteroaryl halides with N-methyliminodiacetic acid (MIDA) boronates is developed. The reaction is performed in water as the sole medium and allows the preparation of a variety of heterobiaryls in excellent yields.

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