Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2013-07-01

Journal: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Included Journals: Scopus、SCIE

Volume: 2013

Issue: 20

Page Number: 4345-4350

ISSN: 1434-193X

Key Words: Cross-coupling; Heterogeneous catalysis; Palladium; Biaryls; Liquid crystals

Abstract: <title content-type="main">Abstract
   An aerobic, ligand-free Suzuki reaction catalyzed by Pd/C in aqueous media has been developed. This method is a very simple, efficient and mild protocol for the cross-coupling of aryl bromides with arylboronic acids, and the reactions proceeded smoothly in excellent yields within short reaction times. Control experiments demonstrated that the Pd/C-catalyzed Suzuki reaction was much quicker when performed in air or oxygen than in nitrogen. Furthermore, this protocol could be used for the synthesis of fluorinated liquid-crystalline compounds. The Pd/C catalyst could be recovered and recycled efficiently at least ten times without significant loss of catalytic activity.