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Indexed by:期刊论文

Date of Publication:2013-06-01

Journal:ASIAN JOURNAL OF ORGANIC CHEMISTRY

Included Journals:SCIE、Scopus

Volume:2

Issue:6

Page Number:514-518

ISSN No.:2193-5807

Key Words:heterogeneous catalysis; ligand-free; oxygen; palladium; Suzuki reaction

Abstract:We report a practical and highly efficient protocol for the synthesis of heterobiaryls by a Pd/C-catalyzed Suzuki reaction under aqueous, aerobic, and ligand-free conditions. This ligand-free catalytic system tolerates a broad range of functional groups in both coupling partners. A variety of heteroaryl halides were coupled with arylboronic acids to give the corresponding heterobiaryls in good to excellent yields. Moreover, the results demonstrated that the Pd/C-catalyzed heterogeneous Suzuki reaction is promoted by oxygen.