Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2013-06-01

Journal: ASIAN JOURNAL OF ORGANIC CHEMISTRY

Included Journals: Scopus、SCIE

Volume: 2

Issue: 6

Page Number: 514-518

ISSN: 2193-5807

Key Words: heterogeneous catalysis; ligand-free; oxygen; palladium; Suzuki reaction

Abstract: We report a practical and highly efficient protocol for the synthesis of heterobiaryls by a Pd/C-catalyzed Suzuki reaction under aqueous, aerobic, and ligand-free conditions. This ligand-free catalytic system tolerates a broad range of functional groups in both coupling partners. A variety of heteroaryl halides were coupled with arylboronic acids to give the corresponding heterobiaryls in good to excellent yields. Moreover, the results demonstrated that the Pd/C-catalyzed heterogeneous Suzuki reaction is promoted by oxygen.