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论文类型：期刊论文
发表时间：2019-10-01
发表刊物：ACTA MECHANICA SINICA
收录刊物：EI、SCIE
卷号：35
期号：5
页面范围：1120-1129
ISSN号：0567-7718
关键字：Lateral aneurysm; In vitro experiment; Pulsatile flow; Wall displacement oscillation; Fluid-structure interaction simulation
摘要：This study experimentally and numerically investigated the effect of pulsatile flow of different frequencies and outflow resistance on wall deformation in a lateral aneurysm. A method for constructing a flexible aneurysm model was developed, and a self-designed piston pump was used to provide the pulsatile flow conditions. A fluid-structure interaction simulation was applied for comparison with and analysis of experimental findings. The maximum wall displacement oscillation increased as the pulsation frequency and outflow resistance increased, especially at the aneurysm dome. There is an obvious circular motion of the vortex center accompanying the periodic inflow fluctuation, and the pressure at the aneurysm dome at peak flow increased as the pulsatile flow frequency and terminal flow resistance increased. These results could explain why abnormal blood flow with high frequency and high outflow resistance is one of the risk factors for aneurysm rupture.