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论文类型：期刊论文

发表时间：2017-07-14

发表刊物：JOURNAL OF MATERIALS CHEMISTRY B

收录刊物：SCIE、EI、Scopus

卷号：5

期号：26

页面范围：5278-5283

ISSN号：2050-750X

摘要：Near-infrared (NIR) fluorescence imaging technology calls for highly bright and photostable emissive materials for long-term and real-time bioimaging and medical diagnosis. Herein, we report that four aminocyanine dyes were covalently encapsulated inside silica nanoparticles by reverse microemulsion using different linkage methods. The fluorescence brightness and photostability of the obtained fluorescent silica nanoparticles (FSNPs) were found to have direct correlation with the used covalent encapsulation methods, especially the number of anchoring sites of the encapsulated dyes. The aminocyanine dye 4-Si contains three anchoring sites for embedding into the silica nanoparticles, and provides FSNP-4- the FSNP with the best brightness and photostability.