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李广哲
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教授
博士生导师
硕士生导师
- 性别：男
- 毕业院校：日本东北大学
- 学位：博士
- 所在单位：化工学院
- 学科：药物化学. 药物工程
- 办公地点：大连理工大学西校区化工综合实验楼G313
- 电子邮箱：liguangzhe@dlut.edu.cn
访问量：
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[1] Shao, Yujie, Miura, Kazuki, Asawa, Yasunobu, Morita, Taiki, 李广哲, Nakamura, Hiroyuki.Discovery of Disubstituted Carboranes as Inhibitors of Heat Shock Protein 90-Heat Shock Factor 1 Int[J],ACS MEDICINAL CHEMISTRY LETTERS,2024
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[2] 王阳, 杨泽家, 王瑞敏, 刘旺, 宿建龙, 张小麦, 张冠一, 吴志豪, Wang, Xu, Chengdong, Sun, Fangfang, 赵伟杰, Xuejian, 彭孝军, 邵堃, 李广哲, Liu, Yiming, Li, Jinrong, Zhang, Yuxuan.Spatiotemporal Controllable Sono-Nanovaccines Driven by Free-Field Based Whole-Body Ultrasound for P[J],Advanced Science,2024
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[3] 张逸, 郭修晗, 曹雷, 李广哲, 李悦青, 赵伟杰.钝顶螺旋藻主成分CHC的立体结构研究[J],昆明理工大学学报(自然科学版),2021,45(5):105-109
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[4] 姜丁宁, 李悦青, 郭修晗, 李广哲, 王世盛, 赵伟杰.果糖嗪的合成及抗衰老评价[J],精细化工,2021,38(8):1644-1649
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[5] 郭修晗, 于昊泽, 申万洁, 蔡蕊, 李悦青, 李广哲, 赵伟杰, 王世盛.Synthesis and biological evaluation of NO-donor containing photosensitizers to induce ferroptosis of[J],Bioorganic Chemistry,2021,116:105355-105355
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[6] 王世盛, 李广哲, 王旭, 邵玉洁, 邵堃, 王阳, 郭修晗, 董慧娟, 赵伟杰, 李悦青.Synthesis and evaluation of 3-(phenylethynyl)-1,1′-biphenyl-2-carboxylate derivatives as new HIF-1 [J],Bioorganic Chemistry,2021,116:105298-105298
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[7] 李广哲, 刘乃碹, 张敬东, 赵伟杰, Hiroyuki Nakamura, 邵玉洁, 潘悦, 李悦青, 王阳, 王柳, 王旭, 邵堃, 王世盛.Total synthesis and biological evaluation of 7-Hydroxyneolamellarin A as hypoxia-inducible factor-1[J],Bioorganic & Medicinal Chemistry Letters,2021,50:128388-128388
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[8] 王柳, 孙芳芳, 杜雪梅, 苏江安, Li Qing, 彭孝军, 邵堃, 赵伟杰, 李广哲, 曹雷, 董伊, 王阳, 王世盛, 李悦青, 郭修晗, 张逸.An Ultrasound-Driven Immune Boosting Molecular Machine for Systemic Tumor Suppression[J],SCIENCE ADVANCES,2021,7(43):4796-4796
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[9] 高志刚, 罗勇, 邓权锋, 李晓瑞, 李广哲.面向组织工程实验的3D生物打印机研制及应用[J],实验室研究与探索,2021,40(1):5-8
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[10] Guo, Xiuhan, 王世盛, Zhang, Fan, 李广哲, Li, Yueqing, Zhao, Weijie.Derivatization of chlorin e6 with maleimide enhances its photodynamic efficacy in HepG2 cells[J],JOURNAL OF PORPHYRINS AND PHTHALOCYANINES,2021,24(9):1093-1098
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[11] 高志刚, 王世盛, 李广哲, 汪晴, 孟庆伟, 叶俊伟.基于OBE理念的制药工程创新人才培养体系改革探索[J],化工高等教育,2021,*(174):33-38
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[12] 王世盛, 张巧丽, 初鹏, 李广哲, 李悦青, 杨丽, 赵伟杰, 郭修晗.Synthesis and antitumor activity of α,β-unsaturated carbonyl moietycontaining oleanolic acid deriv[J],BIOORGANIC CHEMISTRY,2021,101
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[13] Dong, Yi, 李广哲, Wang, Liu, Cao, Lei, 李悦青, 赵伟杰.Anti-tumor evaluation of a novel methoxyphenyl substituted chlorin photosensitizer for photodynami[J],JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,2021,211
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[14] Wang, Shi-Sheng, Tang, Ze-Yao, Zhang, Qiao-Li, Chu, Peng, Kong, Ling-Qi, Li, Guang-Zhe, Yue-Qing, Yang, Li, Zhao, Wei-Jie, Guo, Xiu-Han, XH (corresponding author), Dalian Univ Technol, Sch Chem Engn, Dept Pharm, Dalian 116024, Peoples R China., Tang, ZY (corresponding author), Dalian Med Univ, Dept Pharmacol, Dalian 116044.Synthesis and antitumor activity of alpha,beta-unsaturated carbonyl moiety-containing oleanolic ac[J],BIOORGANIC CHEMISTRY,2020,101
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[15] Li, Guangzhe, Wang, Chengdong, Yueqing, Shao, Kun, Yu, Guo, Shisheng, Guo, Xiuhan, Zhao, Weijie, Nakamura, Hiroyuki, GZ (corresponding author), Dalian Univ Technol, Sch Chem Engn, Dept Pharm, 2 Linggong Rd, Dalian 116024, Peoples R China., Li, State Key Lab Fine Chem.Zinc(ii)-catalyzed intramolecular hydroarylation-redox cross-dehydrogenative coupling ofN-propargy[J],CHEMICAL COMMUNICATIONS,2020,56(53):7333-7336
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[16] Li, Mingle, Pu, Zhongji, Huang, Haiqiao, Xiong, Tao, Kang, Yao, Guangzhe, Zhao, Xueze, Peng, Xiaojun, Shao, Yujie, Kim, Ji Hyeon, Kun, Fan, Jiangli, Foley, James W., Jong Seung, XJ (reprint author), Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China., Peng, Shenzhen Res Inst, Kim, JS (reprint author), Korea Univ, Dept Chem, Seoul 02841, South Korea..Unimolecular Photodynamic O-2-Economizer To Overcome Hypoxia Resistance in Phototherapeutics[J],JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2020,142(11):5380-5388
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[17] Li Mingle, Shao Kun, Fan Jiangli, Foley James W, Kim Jong Seung, Peng Xiaojun, Shao Yujie, Kim Ji Hyeon, Pu Zhongji, Zhao Xueze, Huang Haiqiao, Xiong Tao, Kang Yao, Li Guangzhe.Unimolecular Photodynamic O2-Economizer To Overcome Hypoxia Resistance in Phototherapeutics[J],Journal of the American Chemical Society,2020,142(11):5380-5388
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[18] Li, Guangzhe, Dong, Huijuan, Shao, Yujie, Zhao, Weijie, Ma, Yao, Kun, Yueqing, Wu, Xiaodan, Wang, Shisheng, SS (reprint author), Dalian Univ Technol, Dept Pharm, Sch Chem Engn, Dalian 116023, Peoples R China..Structure-activity relationships study of neolamellarin A and its analogues as hypoxia inducible f[J],BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2019,29(16):2327-2331
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[19] Li Guangzhe, Nakamura Hirouki.Synthesis of 2-Indolyltetrahydroquinolines by Zinc(II)-Catalyzed Intramolecular Hydroarylation-Redox[J],Angew. Chem. Int. Ed.,2016,55(23):6758-6761
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[20] Li, Yue-qing, Wu, Qian-qian, Zhao, Wei-jie, Guang-zhe, Dong, Yi, Ma, Xu, Hui-juan.Orobanone analogues from acid-promoted aromatization rearrangement of curcumol inhibit hypoxia-ind[J],BIOORGANIC CHEMISTRY,2019,85:357-363
