Release Time:2020-04-09  Hits:

Indexed by: Journal Papers

Date of Publication: 2020-03-01

Journal: JOURNAL OF HETEROCYCLIC CHEMISTRY

Included Journals: SCIE

Volume: 57

Issue: 3

Page Number: 955-964

ISSN: 0022-152X

Abstract: An efficient, silver-based catalytic system has been designed for the synthesis of biologically important 3-aminoimidazo-fused heterocycles via the Groebke-Blackburn-Bienayme reaction, in which AgOAc was used as a catalyst and ethylene glycol as a solvent from isocyanides, various aryl aldehydes and an 2-amino heterocycle were also used. Good to excellent yields, high atomic economy and environmentally friendly conditions are the potential features of this one-pot process.