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Indexed by:Journal Papers

Date of Publication:2020-03-01

Journal:JOURNAL OF HETEROCYCLIC CHEMISTRY

Included Journals:SCIE

Volume:57

Issue:3

Page Number:955-964

ISSN No.:0022-152X

Abstract:An efficient, silver-based catalytic system has been designed for the synthesis of biologically important 3-aminoimidazo-fused heterocycles via the Groebke-Blackburn-Bienayme reaction, in which AgOAc was used as a catalyst and ethylene glycol as a solvent from isocyanides, various aryl aldehydes and an 2-amino heterocycle were also used. Good to excellent yields, high atomic economy and environmentally friendly conditions are the potential features of this one-pot process.