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刘宇博
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教授
博士生导师
硕士生导师
- 任职 : 智能生物制造教育部重点实验室
- 性别：男
- 毕业院校：大连理工大学
- 学位：博士
- 所在单位：化工海洋与生命学院
- 学科：生物化学与分子生物学. 生物化工. 化学生物学
- 办公地点：大连理工大学 智能生物制造教育部重点实验室 生命科学与药学系
- 联系方式：liuyubo@dlut.edu.cn
- 电子邮箱：liuyubo@dlut.edu.cn
访问量：
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[81] 刘宇博, 张娜娜, 陈锦娇, 朱彤, 张嘉宁, 李文利, Li, WL (reprint author), Dalian Univ Technol, Sch Life Sci & Med, Panjin 124221, Peoples R China..O-连接N-乙酰葡糖胺转移酶抑制剂的筛选与活性分析[J],高等学校化学学报,2018,39(06):1185-1190
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[82] Liu Y., Cao Y., Pan X., Shi M., Wu Q., Huang T., Jiang H., Li W., Zhang J., Zhang, J., School of Life Science, Medicine, Dalian University of TechnologyChina, email: jnzhang@dlut.edu.cn.O-GlcNAc elevation through activation of the hexosamine biosynthetic pathway enhances cancer cell ch[J],Cell death & disease,2018,9(5)
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[83] 刘宇博, 张娜娜, 陈锦娇, 朱彤, 张嘉宁, 李文利.Discovery and Activity Verification of a O-GlcNAc Transferase Inhibitor by Structure-based Virtual S[J],Chemical Journal of Chinese Universities,2018,39:1185-1190
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[84] 史艳丽, 刘宇博, 吴思晋, 刘亚军, 张嘉宁, 李文利.Virtual Screening and Activity Verification of Novel Inhibitors of Apiv 3c Protease.[J],Chemical Journal of Chinese Universities,2018,39:701-707
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[85] Huang, Huang, Liu, Yubo, Yu, Peishan, Qu, Jianhua, Guo, Yanjie, Li, Wenli, Wang, Shujing, Zhang, Jianing, JN (reprint author), Dalian Univ Technol, Sch Life Sci & Med, Panjin, Peoples R China..MiR-23a transcriptional activated by Runx2 increases metastatic potential of mouse hepatoma cell via[J],Scientific reports,2018,8(1):7366
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[86] 史艳丽, 刘宇博, 吴思晋, 刘亚军, 张嘉宁, 李文利, Li, WL (reprint author), Dalian Univ Technol, Sch Life Sci & Med, Panjin 124221, Peoples R China..ApIV 3C蛋白酶抑制剂的虚拟筛选及活性测定[J],高等学校化学学报,2018,39(4):701-707
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[87] Liu, Yubo, Ren, Yang, Cao, Yu, Huang, Huang, Wu, Qiong, Li, Wenli, Sijin, Zhang, Jianing, JN (reprint author), Dalian Univ Technol, Sch Life Sci & Med, Panjin, Peoples R China..Discovery of a Low Toxicity O-GlcNAc Transferase (OGT) Inhibitor by Structure-based Virtual Screen[J],SCIENTIFIC REPORTS,2017,7(1):12334
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[88] 吴琼, 张程, 黄天淼, 黄煌, 刘宇博, 李文利, 张嘉宁.ppGaINAc-T4调控人乳腺癌细胞转移潜能[A],2017,1
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[89] 黄天淼, 吴琼, 张程, 黄煌, 刘宇博, 李文利, 张嘉宁.N-乙酰氨基半乳糖转移酶8通过调控C1GALT1和COMSC影响乳腺癌的O-GalNAc糖基化修饰[A],2017,1
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[90] 张程, 吴琼, 黄天淼, 黄煌, 刘宇博, 李文利, 张嘉宁.小鼠肝癌细胞中Caveolin-1通过JNK、p38、ERK信号转导途径调控pofut1表达[A],2017,1
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[91] Liu, Yubo, Huang, Huang, Meijun, Wu, Qiong, Li, Wenli, Zhang, Jianing, JN (reprint author), Dalian Univ Technol, Sch Life Sci & Med, Panjin 122406, Peoples R China..MicroRNA-24-1 suppresses mouse hepatoma cell invasion and metastasis via directly targeting O-GlcN[J],BIOMEDICINE & PHARMACOTHERAPY,2017,91:731-738
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[92] Liu, Yubo, Huang, Huang, Cao, Yu, Wu, Qiong, Li, Wenli, Zhang, Jianing, JN (reprint author), Dalian Univ Technol, Sch Life Sci & Med, Panjin 122406, Peoples R China..Suppression of OGT by microRNA24 reduces FOXA1 stability and prevents breast cancer cells invasion[J],BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2017,487(3):755-762
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[93] 徐品三, 张郑瑶, 刘宇博.Visible Study of Mercuric Ion in Brassica Juncea Living Cells and Plants Using a Fluorescent Dye[J],Advances in Biological Sciences Research,2017,4:107-112
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[94] 徐品三, 刘宇博, 张郑瑶.Visible Study of Mercuric Ion in Brassica Juncea Living Cells and Plants Using a Fluorescent Dye[A],2017
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[95] Wang, Anhui, Song, Ting, Ziqian, Liu, Yubo, Fan, Yudan, Zhang, Yahui, Zhichao, ZC (reprint author), Dalian Univ Technol, Sch Chem, State Key Lab Fine Chem, Dalian 116024, Peoples R China..Mechanism of Mcl-1 Conformational Regulation Upon Small Molecule Binding Revealed by Molecular Dyn[J],CHEMICAL BIOLOGY & DRUG DESIGN,2016,87(4):551-561
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[96] Song, Ting, Chai, Gaobo, Liu, Yubo, Yu, Xiaoyan, Wang, Ziqian, Zhang, Zhichao, ZC (reprint author), Dalian Univ Technol, Sch Chem, State Key Lab Fine Chem, Dalian 116024, Peoples R China..Bcl-2 phosphorylation confers resistance on chronic lymphocytic leukaemia cells to the BH3 mimetic[J],BRITISH JOURNAL OF PHARMACOLOGY,2016,173(3):471-483
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[97] Song, Ting, Chai, Gaobo, Liu, Yubo, Xie, Mingzhou, Chen, Qingbin, Yu, Xiaoyan, Sheng, Hongkun, Zhang, Zhichao, ZC (reprint author), Dalian Univ Technol, Sch Chem, State Key Lab Fine Chem, Dalian, Peoples R China..Mechanism of synergy of BH3 mimetics and paclitaxel in chronic myeloid leukemia cells: Mcl-1 inhib[J],EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,2015,70:64-71
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[98] Song, Ting, Yu, Xiaoyan, Liu, Yubo, Li, Xiangqian, Chai, Gaobo, Zhang, Zhichao, ZC (reprint author), Dalian Univ Technol, State Key Lab Fine Chem, Sch Chem, Dalian 116024, Peoples R China..Discovery of a Small-Molecule pBcl-2 Inhibitor that Overcomes pBcl-2-Mediated Resistance to Apopto[J],CHEMBIOCHEM,2015,16(5):757-765
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[99] Liu, Yubo, Xie, Mingzhou, Song, Ting, Sheng, Hongkun, Yu, Xiaoyan, Zhang, Zhichao, ZC (reprint author), Dalian Univ Technol, Sch Chem, State Key Lab Fine Chem, Dalian, Peoples R China..A novel BH3 mimetic efficiently induces apoptosis in melanoma cells through direct binding to anti[J],PIGMENT CELL & MELANOMA RESEARCH,2015,28(2):161-170
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[100] Huang, Xing, Zhang, Zhichao, Wang, Chuang, Li, Song, Liu, Yubo, ZC (reprint author), Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116012, Peoples R China..Highly Sensitive Visualization of Inorganic Mercury in Mouse Neurons Using a Fluorescent Probe[J],JOURNAL OF FLUORESCENCE,2014,24(4):1313-1317
