李学召
Associate Professor Supervisor of Doctorate Candidates Supervisor of Master's Candidates
Gender:Male
Alma Mater:大连理工大学
Degree:Doctoral Degree
School/Department:化学学院
Discipline:Inorganic Chemistry. Chemical Biology
Business Address:化学学院海晖楼117B
E-Mail:xuezhaoli@dlut.edu.cn
2012.9 -- 2016.12
大连理工大学  化学工程与技术(精细化工)  Doctoral Degree
2010.9 -- 2012.6
大连理工大学  化学工程  Master's Degree
2020.6 -- Now
大连理工大学张大煜学院 副研究员
2017.1 -- 2020.6
大连理工大学 博士后
李学召 副研究员 博导、硕导
2020年6月加入化学学院张大煜分子科学研究中心。
主持国家自然科学基金面上项目(2024年,2021年)、青年项目(2017年)、第63批中国博士后科学基金面上项目(一等)、辽宁省博士启动基金项目;参与两项国家自然科学基金国际(地区)合作与交流项目。入选大连市青年才俊、引进城市发展紧缺人才(五星)、大连理工大学“星海骨干”计划支持。在Coord. Chem. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Mater.等国际知名期刊发表学术论文多篇,部分文章入选杂志封面或背封面。
手性超分子组装与光疗
研究方向
手性光活性功能金属-有机超分子结构可控组装-仿生识别分离与不对称光催化
手性超分子螺旋体与生物大分子特异性识别机制、生物学效应探究与疾病诊疗
欢迎具有配位化学、超分子化学、特别是化学生物学背景,对课题组研究方向感兴趣的博后、博硕研究生,本科生加入!
代表性论文发表
2023年
(14) Xuezhao Li,* Xing Zhao, Wen Wang, Zhuolin Shi, Yangming Zhang, Qingqing Tian, Yougang Yao, Cheng He, Chunying Duan,* Biomedical applications of multinuclear Pt(II)/Ru(II)/Ir(III) metallo-supramolecular assemblies for intensive cancer therapy, Coord. Chem. Rev., 2023, 495, 215366.
(13) Xuezhao Li,* Zhicheng Wang, Xiaorou Hao, Jingyi Zhang, Xing Zhao, Yougang Yao, Wei Wei, Rui Cai, Cheng He, Chunying Duan,* Zijian Guo, Jing Zhao,* and Xiuxiu Wang*, Optically Pure Double-Stranded Dinuclear Ir(III) Metallohelices Enabled Chirality-Induced Photodynamic Responses, J. Am. Chem. Soc., 2023, 145, 14766-14775.
(12) Guangli He, Maomao He, Ran Wang, Xuezhao Li,* Hanze Hu, Dongsheng Wang, Ziqian Wang, Yang Lu, Ning Xu, Jianjun Du, Jiangli Fan, Xiaojun Peng, Wen Sun*, A Near-Infrared Light-Activated Photocage Based on a Ruthenium Complex for Cancer Phototherapy, Angew. Chem. Int. Ed., 2023, 62, e202218768.
2022年
(11) Jinguo Wu, Xuezhao Li,* Zhuolin Shi, Cheng He*, Single-Crystal-to-Single-Crystal Transformation and Alcohols Enantioseparation of Homochiral Ir(III)-Metallohelix-Based Porous Molecular Crystal, Eur. J. Inorg. Chem., 2022, 27, e202200351.
(10) Jinguo Wu, Xuezhao Li,* Pengyan Wu, Zhuolin Shi, Liyong Chen, Rong Zhang, Cheng He,* and Chunying Duan*, Engineering Homochiral Dinuclear-Ir(III)-Metallohelices-based Porous Molecular Crystals for Atropisomers Enantioseparation, Chem. Mater., 2022, 10, 4471-4478.
2021年
(9) Yuchao Li, Xuezhao Li,* Lili Li, Bing Xiao, Jinguo Wu, Hechuan Li, Danyang Li, Cheng He*, Phenoxazine-based supramolecular tetrahedron as biomimetic lectin for glucosamine recognition, Chin. Chem. Lett., 2021, 32, 735-739.
2020年
(8) Shuhua Cao, Xuezhao Li,* Yong Gao, Fahui Li, Kaoxue Li, Xuanxuan Cao, Yiwen Dai, Lirong Mao, Shanshan Wang and Xishi Tai*, A simultaneously GSH-depleted bimetallic Cu(II) complex for enhanced chemodynamic cancer therapy, Dalton Trans., 2020, 49, 11851-11858.
(7) Xuezhao Li, Zhuolin Shi, Jinguo Wu, Jinlong Wu, Cheng He,* Xiaorou Hao and Chunying Duan,* Lighting up metallohelices: from DNA binders to chemotherapy and photodynamic therapy, Chem. Commun., 2020, 56, 7537-7548.
(6) Xuezhao Li,# Jinguo Wu,# Lei Wang, Cheng He,* Liyong Chen, Yang Jiao, and Chunying Duan,* Mitochondrial-DNA-targeted IrIII-Containing Metallohelices with Tunable Photodynamic Therapy Efficacy in Cancer Cells, Angew. Chem. Int. Ed., 2020, 59, 6420-6427.
(5) Tianchi Feng, Xuezhao Li,* Jinguo Wu, Cheng He, Chunying Duan, Cavity-directed nitroaromatics sensing within a carbazole-based luminescent supramolecular M2L3 cage, Chin. Chem. Lett., 2020, 31, 95-98.
Before 2020年
(4) Xuezhao Li, Jinguo Wu, Cheng He, Qingtao Meng, Chunying Duan,* Asymmetric Catalysis within the Chiral Confined Space of Metal-Organic Architectures, Small, 2019, 15, 1804770.
(3) Hailing Wang, Lili Li, Xuezhao Li,* Cheng He, Encapsulation of organic dyes within an Electron-deficient redox metal−organic tetrahedron for photocatalytic proton reduction, Isr. J. Chem., 2019, 59, 273-279.
(2) Xuezhao Li, Jinguo Wu, Liyong Chen, Xiaoming Zhong, Cheng He,* Rong Zhang, Chunying Duan, Engineering an iridium-containing metal–organic molecular capsule for induced-fit geometrical conversion and dual catalysis, Chem. Commun., 2016, 52, 9628-9631.
(1) Xuezhao Li, Jinguo Wu, Cheng He,* Rong Zhang, Chunying Duan, Multicomponent self-assembly of a pentanuclear Ir-Zn heterometal-organic polyhedron for carbon dioxide fixation and sulfite sequestration, Chem. Commun., 2016, 52, 5104-5107.
学术报告
7. 2024, 8.22-8.25
口头报告,第十七届生物无机化学会议暨金属化学生物学学术会议,无机药物化学分会。
中国,武汉
李学召 双核铱(III)螺旋结构光动力癌症治疗
6. 2024, 6.15-6.18
口头报告,中国化学会第34届学术年会,L05:配位化学前沿交叉论坛。
中国,广东
李学召 程序化组装Ir(III)基光敏螺旋结构抗肿瘤活性研究
5. 2023, 6.17-6.20
邀请报告,中国化学会第33届学术年会,生物无机化学分会。
中国,青岛
李学召 双核Ir(III)螺旋结构手性调控----生物大分子特异性识别与光动力治疗
4. 2022, 6.17-6.20
口头报告,第九届全国配位化学会议。
中国,郑州
李学召 DNA靶向(手性)双核Ir(III)螺旋结构光动力治疗
3. 2021, 4.19-4.22
口头报告,中国化学会第32届学术年会,生物无机化学分会。
中国,珠海
李学召 “结构本征”靶向DNA双核Ir(III)螺旋体光动力癌症治疗
2. 2018, 7.29-8.04
邀请报告,第43届国际配位化学会议,S43 Chiral Functional Materials 分会。
日本,仙台
李学召 “Chiral Self-Sorting during Helicates Formation Based on Stereochemically 'pre-programmed' Ir(III) Modules”
1. 2017, 10.19-10.22
口头报告,第8届全国配位化学会议。
中国,大连
李学召 “Heterometallic Ir(III) Complexes Containing MOP: Construction and Properties”