点击次数：

论文类型：期刊论文

发表时间：2020-08-01

发表刊物：MARINE POLLUTION BULLETIN

收录刊物：SCIE

卷号：157

ISSN号：0025-326X

关键字：Gonyautoxins 2&3; LC-HAMS; Molecularly imprinted solid-phase extraction; Seawater sample; Liaodong Bay

摘要：Paralytic shellfish toxins (PSTs) cause risks to human health through food chains. Understanding the change of PSTs in seawater is critical for predicting the safety of seafood. Most reported methods for the detection of PSTs in microalgae or shellfish are not applicable in seawater because of extremely low concentration and matrix interferences. High resolution mass spectrometry (HAMS), quadrupole exactive orbitrap detects molecular ions accurately, and molecularly imprinted solid-phase extraction (MISPE) is recognized effective to reduce the matrix interference. GTXs 2&3 are two of common marine toxins in PSTs. In this study, a sensitive method consisting MISPE and liquid chromatography LC-HAMS was developed for the detection of GTXs 2&3 with a limit of detection (LOD) of 47.4 ng/L in seawater. With this method, samples obtained from the estuaries of the Shuangtaizi and Daliao Rivers were analyzed, and the results indicated the concentrations were lower than LOD in the area under investigation.