生物医用材料表界面精准功能调控

重症血液净化

精准细菌调控

科研论文

第一/通讯作者

10. Z.H. Li#, L.Q. Jin#, X.J. Yang, H. Liu, S.X. Qian, Z.H. Wang, J.Q. Liu, J.X. Wang, J.J. Chen, B.H. Su, C.R. Peng, J.C. Wang*, Z.Q. Shi*. A Multifunctional Ionic Liquid Coating on 3D-Printed Prostheses: Combating Infection, Promoting Osseointegration. Materials Today Bio. 2024; 26: 101076. 

9.  Z.Q. Shi, X.C. Zhang, X.J. Yang, X.Y. Zhang, F. Ma, H. Gan, J.J. Chen, D.D. Wang, W.J. Sun, J.X. Wang, C.L. Wang, L.T. Lyu, K.G. Yang, L.J. Deng, G.Y. Qing*. Specific Clearance of Lipopolysaccharide from Blood Based on Peptide Bottlebrush Polymer for Sepsis Therapy. Advanced Materials. 2023; 35 (33): 2302560.

8.  J.J. Chen, Z.Q. Shi*, X.J. Yang, X.Y. Zhang, D.D. Wang, W.J. Sun, J.X. Wang, C.L. Wang, Q.Y. Li, Z.J. Wang, Y.L. Song*, G.Y. Qing*. Broad-Spectrum Clearance of Lipopolysaccharides from Blood Based on a Hemocompatible Dihistidine Polymer. ACS Applied Materials & Interfaces. 2023, 15(27): 32251-32261.

7.  孙文静, 施振强*, 卿光焱. 循环肿瘤细胞捕获材料的研究进展[J]. 色谱, 2021; 39(10): 1041-1044.

6.  Z.Q. Shi, L.Q. Jin, C. He, Y.P. Li, C.J. Jiang, H. Wang, J. Zhang, J.X. Wang, W.F. Zhao*, C.S. Zhao*. Hemocompatible Magnetic Particles with Broad-spectrum Bacteria Capture Capability for Blood Purification. Journal of Colloid and Interface Science. 2020; 576: 1-9.

5.  Z.Q. Shi, Y. Zhang, R. Dai, S.Q. Chen, M. Zhang, W.F. Zhao*, C.S. Zhao*. Rationally Designed Magnetic Poly(catechol-hexanediamine) Particles for Bacteria Removal and On-demand Biofilm Eradication. Colloids and Surfaces B: Biointerfaces. 2020; 186: 110728.

4.  R. Dai, Y. Zhang, Z.Q. Shi*, F. Yang, C.S. Zhao*. A Facile Approach Towards Amino-coated Ferroferric Oxide Nanoparticles for Environmental Pollutant Removal. Journal of Colloid and Interface Science. 2018; 513: 647-657.

3.  Z.Q. Shi, Y.T. Cai, J. Deng, W.F. Zhao*, C.S. Zhao*. Host-Guest Self-Assembly Toward Reversible Thermo-Responsive Switching for Bacteria Killing and Detaching. ACS Applied Materials & Interfaces. 2016; 8 (36): 23523-23532.

2.  Z.Q. Shi, H.F. Ji, H.C. Yu, X.L. Huang, W.F. Zhao, S.D. Sun*, C.S. Zhao*. Engineering Polyethersulfone Hollow Fiber Membrane with Improved Blood Compatibility and Antibacterial Property. Colloid and Polymer Science. 2016; 294: 441-453.

1.  Z.Q. Shi, X.L. Huang, C. Wang, Y.F. Li, C. He*, C.S. Zhao*. In Situ Cross-Linked Polymerization toward Poly (ether sulfone)/Poly (sodium acrylate) Hybrid Particles for the Removal of Environmental Toxins. Industrial & Engineering Chemistry Research. 2014; 53: 14084-14093.

其他

29.  Y. Li, Y. Sun, X.Y. Zhang, D.D. Wang, X.D. Yang, H.J. Wei, C.L. Wang, Z.Q. Shi, X.N Li, F.L. Zhang, W.J. Sun, Z.Y. Yang, Y.L. Song*, G.Y. Qing*. Selective Clearance of Circulating Histones Based on Dodecapeptide-Grafted Copolymer Material for Sepsis Blood Purification. ACS Applied Materials & Interfaces. 2024. DOI: 10.1021/acsami.4c07494.

28. Y. Sun, X. Wang, X.Y. Zhang*, Y. Li, D.D. Wang, F. Sun, C.L. Wang, Z.Q. Shi, X.D. Yang, Z.Y. Yang, H.J. Wei, Y.L. Song*, G.Y. Qing*. Di-Caffeoylquinic Acid: A Potential Inhibitor for Amyloid-Beta Aggregation. Journal of Natural Medicines. 2024; 1-15. 

27. X.P. Li, Y.J. Zhang, Z.Q. Shi, D.D. Wang, H. Yang, Y.H. Zhang, H.J. Qin, W.Q. Lu, J.J. Chen, Y. Li, G.Y. Qing*. Water-Stable Boroxine Structure with Dynamic Covalent Bonds. Nature Communications. 2024; 15(1): 1-12.

26.  C.L. Wang, Y.M. Yang, X.Y. Zhang, Z.Q. Shi, H.L. Gao, M.L. Zhong, Y.G. Fan, H.Y. Zhang, B. Liu*, G.Y. Qing*. Secreted Endogenous Macrosomes Reduce Aβ Burden and Ameliorate Alzheimer's Disease. Science Advances. 2023; 9(21): eade0293.

25. J. Xiao, Z.Q. Shi, M.Y. Cong, D.D. Wang, H.J. Qin, Q.Y. Li, W.Q. Lu, Z.M. Guo, X.M. Liang, G.Y. Qing. Photoswitchable Nanoporous Metal–Organic Framework Monolayer Film for Light-Gated Ion Nanochannel. ACS Applied Nano Materials. 2023; 6: 2813-2821.

24. J.X. Wang, C.R. Peng, X.J. Yang, M.J. Ni, X.B. Zhang, Z.Q. Shi, H. Chen, S.Y. Liu, L.Q. Jin, C.S. Zhao*. Lysozyme-Immobilized Polyethersulfone Membranes with Satisfactory Hemocompatibility and High Enzyme Activity for Endotoxin Removal. Biomacromolecules. 2023; 24(9): 4170-4179

23. Y.H. Zhang, X.Y. Zhao, Y. Qin, X.P. Li, Y.X. Chang, Z.Q. Shi, M.Y. Song, W.J. Sun, J. Xiao, Z. Li, G.Y. Qing*. Order–Order Assembly Transition-Driven Polyamines Detection Based on Iron−Sulfur Complexes. Communications Chemistry. 2023; 6 (1): 146.

22.  J.N. Sun, K.W. Wang, R.N. Hao, Z.Y. Zhang, Z.Y. Feng, Z.Q. Shi, W.J. Yuan, Z.Y. Jing, L. Zhang*. Disregarded Free Chains Affect Bacterial Adhesion on Cross-linked Polydimethylsiloxane Surfaces. ACS Applied Materials & Interfaces. 2023, 15(30): 36936-36944.

21.  X.T. Zheng, F.S. Zhang, Y.Y. Zhao, Y.T. Xiong, X.Y. Zhang, Z.Q. Shi, S.X. Qian, H.J. Qin, G.Y. Qing. Enrichment of IgG and HRP Glycoprotein by Dipeptide-Based Polymeric Material. Talanta. 2022; 241: 123223.

20.  X. Yang, W. Zhang, X.Z. Qin, M.M. Cui, Y.T. Guo, T. Wang, Z.Q. Shi, C. Zhang, W.B. Li, Z.K. Wang, Recent Progress on Bioinspired Antibacterial Surfaces for Biomedical Application. Biomimetics. 2022; 7 (3): 88.

19.  D.D. Wang, T.X. Bai, X. Wang, Y.T. Xiong, Y.H. Zhang, Z.Q. Shi, F.S. Zhang, W.Q. Lu, G.Y. Qing. Sensing Mechanism of Excited‐State Intermolecular Hydrogen Bond for Phthalimide: Indispensable Role of Dimethyl Sulfoxide. Chinese Journal of Chemistry. 2021; 39(5): 1113-1120.

18.  J. Zhang, Z.Q. Shi, C. He*, X. Song, Y. Yang, S.D. Sun, W.F. Zhao, C.S. Zhao*. Urease Immobilized GO Core@Shell Heparin-Mimicking Polymer Beads with Safe and Effective Urea Removal for Blood Purification. International Journal of Biological Macromolecules. 2020; 156: 1503-1511.

17.  J.R. Yin, Z.Q. Shi, L.Q. Jin, X. Song, H.F. Ji, Y. Yang, S.D. Sun, W.F. Zhao*, C.S. Zhao*. Precipitated Droplets In-Situ Cross-Linking Polymerization and Its Applications. Polymer Testing. 2020; 91: 106756.

16.  Y.P. Li, J.M. Li, Z.Q. Shi, Y.L. Wang, X. Song, L.Y. Wang, M. Han, H.Y. Du, C. He, W.F. Zhao, B.H. Su*, C.S. Zhao*. Anticoagulant Chitosan-kappa-Carrageenan Composite Hydrogel Sorbent for Simultaneous Endotoxin and Bacteria Cleansing in Septic Blood. Carbohydrate Polymers. 2020; 243: 116470.

15.  L.Q. Jin, Z.Q. Shi, X. Zhang, X.L. Liu, H.L. Li, J.X. Wang, F. Liang*, W.F. Zhao*, C.S. Zhao*. Intelligent Antibacterial Surface Based on Ionic Liquid Molecular Brushes for Bacterial Killing and Release. Journal of Materials Chemistry B. 2019; 7: 5520-5527.

14.  Y. Xie, S.Q. Chen, X. Zhang, Z.Q. Shi, Z.W. Wei, J.X. Bao, W.F. Zhao*, C.S. Zhao*. Engineering of Tannic Acid Inspired Antifouling and Antibacterial Membranes Through Co-Deposition of Zwitterionic Polymers and Ag Nanoparticles. Industrial & Engineering Chemistry Research. 2019; 58 (27): 11689-11697.

13.  L.Q. Jin, X. Zhang, W.F. Zhao, S.Q. Chen, Z.Q. Shi, J.X. Wang, Y. Xie, F. Liang*, C.S. Zhao*. General Method for Synthesizing Transition-Metal Phosphide/N-Doped Carbon Nanomaterials for Hydrogen Evolution. Langmuir. 2019; 35 (28): 9161-9168.

12.  J.X. Wang, C.R. Peng, Z.P. Chen, S.D. Sun, Z.Q. Shi, L.Q. Jin, W.F. Zhao*, C.S. Zhao*. Engineering Antimicrobial and Biocompatible Electrospun PLGA Fibrous Membranes by Irradiation Grafting Polyvinylpyrrolidone and Periodate. Colloids and Surfaces B: Biointerfaces. 2019; 181: 918-926.

11.  H.F. Ji, X. Song, Z.Q. Shi, C.Q. Tang, L. Xiong, W.F. Zhao*, C.S. Zhao*. Reinforced-Concrete Structured Hydrogel Microspheres with Ultrahigh Mechanical Strength, Restricted Water Uptake, and Superior Adsorption Capacity. ACS Sustainable Chemistry & Engineering. 2018; 6 (5), 5950-5958.

10.  C. Cheng*, J.G. Zhang, S. Li, Y. Xia, C.X. Nie, Z.Q. Shi, J.L. Cuellar‐Camacho, N. Ma, R. Haag*. A Water‐Processable and Bioactive Multivalent Graphene Nanoink for Highly Flexible Bioelectronic Films and Nanofibers. Advanced Materials. 2018; 30 (5): 1705452.

9.  S.Q. Chen, Y. Du, X. Zhang, Y. Xie, Z.Q. Shi, H.F. Ji, W.F. Zhao*, C.S. Zhao*. One-Step Electrospinning of Negatively-Charged Polyethersulfone Nanofibrous Membranes for Selective Removal of Cationic Dyes. Journal of the Taiwan Institute of Chemical Engineers. 2018; 82: 179-188.

8.  Y.T. Xu, D.D. Yuan, J.X. Bao, Y. Xie, M. He, Z.Q. Shi, S.Q. Chen, C. He, W.F. Zhao*, C.S. Zhao*. Nanofibrous Membranes with Surface Migration of Functional Groups for Ultrafast Wastewater Remediation. Journal of Materials Chemistry A. 2018; 6 (27): 13359-13372.

7.  M. Zhang, R. Wang, Z.Q. Shi, X.L. Huang, W.F. Zhao*, C.S. Zhao*. Multi-Responsive, Tough and Reversible Hydrogels with Tunable Swelling Property. Journal of Hazardous Materials. 2017; 322: 499-507.

6.  M. He, Q. Wang, Z.Q. Shi, Y. Xie, W.F. Zhao*, C.S. Zhao*. Inflammation-Responsive Self-Regulated Drug Release from Ultrathin Hydrogel Coating. Colloids and Surfaces B: Biointerfaces. 2017; 158: 518-526.

5.  H.F. Ji, L. Xiong, Z.Q. Shi, M. He, W.F. Zhao*, C.S. Zhao*. Engineering of Hemocompatible and Antifouling Polyethersulfone Membranes by Blending with Heparin-Mimicking Microgels. Biomaterials Science. 2017; 5 (6): 1112-1121.

4.  C. He, Z.Q. Shi, C. Cheng*, C.X. Nie, M. Zhou, L.R. Wang, C.S. Zhao*. Highly Swellable and Biocompatible Graphene/Heparin-Analogue Hydrogels for Implantable Drug and Protein Delivery. RSC Advances. 2016; 6: 71893-71904.

3.  C. He, Z.Q. Shi, C. Cheng*, H.Q. Lu, M. Zhou, S.D. Sun, C.S. Zhao*. Graphene Oxide and Sulfonated Polyanion Co-Doped Hydrogel Films for Dual-Layered Membranes with Superior Hemocompatibility and Antibacterial Activity. Biomaterials Science. 2016; 4: 1431-1440.

2.  C. He, Z.Q. Shi, L. Ma, C. Cheng*, C.X. Nie, M. Zhou, C.S. Zhao*. Graphene Oxide Based Heparin-Mimicking and Hemocompatible Polymeric Hydrogels for Versatile Biomedical Applications. Journal of Materials Chemistry B. 2015;3: 592-602.

1.  C. He, C. Cheng*, H.F. Ji, Z.Q. Shi, L. Ma, Mi Zhou, Changsheng Zhao*. Robust, Highly Elastic and Bioactive Heparin-Mimetic Hydrogels. Polymer Chemistry. 2015; 6 (45), 7893-7901.

专利     

7.  卿光焱, 施振强, 张宪成。一种多肽及其应用。中国发明专利，2023，申请号：202310547326.5

6.  卿光焱, 施振强, 张晓雨。靶向内毒素的功能聚合物和内毒素分离材料及制备与应用。中国发明专利，2023，申请号：202310547325.0

5.  C.S. Zhao, B.H. Su, W.F. Zhao, S.D. Sun, C. Wang, Z.Q. Shi, Q. Liu, X.H. Zhang, P. Fu, J.H. Zhou. Wearable Filtrating Artificial Kidney Device. US Patent No. US10500325B2.

4.  赵长生, 何超, 赵伟锋, 周密, 施振强, 纪海锋, 钱一晖。一种多巴胺接枝磺化海藻酸钠双交联微球及其制备方法和用途。中国发明专利，2018，专利号：ZL201810572503.4

3.  赵长生, 苏白海, 赵伟锋, 孙树东, 王臣, 施振强, 刘强, 张小华, 付平, 周建辉。佩戴式滤过型人工肾装置。中国实用新型专利，2016，专利号：ZL201690001743.3

2.  赵长生, 何超, 施振强, 马朗, 纪海锋, 程冲, 覃慧, 赵伟锋。原位聚合微交联聚丙烯酸钠改性聚醚砜微球及其制备方法和用途。中国发明专利，2014，专利号：ZL201410660527.7

1.  赵长生, 何超, 施振强, 马朗, 聂胜强, 程冲, 覃慧, 赵伟锋。原位聚合微交联聚乙烯吡咯烷酮改性聚醚砜中空纤维膜及其制备方法和用途。中国发明专利，2013，专利号：ZL201310682648.7 

著作

1.  赵长生, 孙树东, 赵伟锋, 张翔, 谢毅, 施振强, 杨晔。生物材料科学与工程丛书”之《生物医用高分子材料》，第18章：血液净化用膜材料，科学出版社