教授/研究员(2016---, Professor in Chemical/Biomedical Engineering)；博导(2014---, Doctoral supervisor in Chemical/Biomedical Engineering)；工学博士(2006, DUT)；帝国理工学院博士后(2008-2009, PDRA in Imperial College London)。2005-2006、2007、2008-2009、2010和2016等分别作为访问学者和博士后赴牛津大学 (Zhanfeng Cui院士)、帝国理工学院(Prof. A. Mantalaris)和悉尼大学(Dr. Yiwei Wang)等进行合作研究。2005-2009，担任长江学者科研助手。

受邀担任国家自然科学基金委生命科学部、中国博士后基金和教育部学位中心等评审专家；TERMIS、ISSCR、IFMBE和中国细胞生物学会会员；中国医促会创伤医学分会组织修复与生物材料学组委员，《中国组织工程研究》学科编委，辽宁省细胞生物学会分子生物学专委会常务理事，辽宁省细胞生物学会中药化学专委会副主委。受邀担任Int J Bioprint (IF=6.8), Curr Cancer Drug Tar (IF=2.3)和Curr Stem Cell Res Ther (IF=2.1)等十余家国际刊物编委，担任Biomaterials, Bioact Mater, Nano-Micro Letters, Chem Eng J, Stem cells, Biofabrication, Acta Biomater和ACS Nano系列等80余家国际知名刊物和生物化学与生物物理进展等4家国内刊物的审稿人。

作为项目负责或子课题负责人，承担完成或正在实施国家自然科学基金面上、青年、国际合作基金七项、霍英东青教基金、省自然科学基金和联合基金、教育部博士点新教师基金和留学回国科研启动基金、校优青人才专项/重大/重点/医工交叉/交叉学科项目专项、企业合作等二十余项。到目前为止在3D打印、生物医用材料、3D动态构建组织工程肿瘤/骨/软骨/血管、造血干/祖细胞3D动态扩增、离子液体环境评价、煤基能源材料等方面已完成系列工作。在Biofabrication, Carbon, Carbohydr Polym, ACS Sustain Chem Eng, J Biol Macromol等TOP期刊发表SCI论文检索150余篇，EI130余篇；被包括Biomaterials (IF=14), Biotechnol. Adv. (IF=16), Chem. Rev. (IF=62.1), Chem. Soc. Rev. (IF=46.2), ACS Nano (IF=17.1), Accounts Chem Res (IF=18.3)等引用近5000次，单篇最高引用902次。申报国家发明专利18项，授权10项，申请国际发明专利1项，获得包括省自然科学优秀成果一等奖等40余项奖励。近年来参加TERMIS World Meeting, EU, AP和NA等系列会议、全国化学工程与生物化工年会，中国医促会学术年会、中国工程院化工、冶金与材料工程学部年会等30余次。

主要研究方向：

1.     干细胞与组织工程(3D生物打印，生物医用材料设计与制备、3D动态构建组织工程肿瘤/骨/软骨/血管/皮肤、造血干/祖细胞3D动态扩增、生物反应器技术等) (学术型、专业型博士/学术型硕士课题)；

2.     离子液体环境评价、煤基能源材料制备、阻燃材料制备等(专业型博士、学术型/工程型硕士，均为企业合作课题)；

3.     其他化工、能源、生物、医学等学科的交叉领域研究(所有博、硕士课题)。

欢迎对上述研究领域感兴趣的同学积极联系报考硕士（鼓励尽早联系，kedongsong@dlut.edu.cn）、博士研究生（务必提前联系，kedongsong@dlut.edu.cn）。考生不限学校、性别、专业、地域，均一视同仁，择优录取。

实验室长期招收博士后，请发送个人简历到kedongsong@dlut.edu.cn。

本课题组部分毕业生工作/深造单位：

所指导博、硕士研究生、本科生累计荣获省/市优秀毕业生、校优硕士/本科毕业论文、国家奖学金等共计200余项奖励。历任化英1001、化1407、化国1901和化国2301班主任，多次获校优秀班主任，所带班级多次获得大连市先进班集体等荣誉。

部分代表性论文（均为通讯作者，中科院一区/TOP/JCR Q1）

1. Song KD*, et al. A 3D bioprinted colorectal tumor model based on decellularized matrix/gelatin methacryloyl/nanoclay/sodium alginate hydrogel. J Biol Macromol. 2024. 2024 Dec 30; 293: 139346.

2. Song KD*, et al. A coaxial 3D bioprinted hybrid scaffold with decellularized extracellular matrix based nano clay/sodium alginate blended bioink for vascular tissue engineering. J Biol Macromol. 2024 Dec 20; 290: 139056.

3. Song KD*, et al. A quercetin nanoparticle combined with a 3D-printed decellularized extracellular matrix/gelatin methacryloyl/sodium alginate biomimetic tumor model for the treatment of melanoma. J Biol Macromol. 2024 Dec 11; 288: 138680.

4. Song KD*, et al. Culturing 3D chitosan/gelatin/nano-hydroxyapatite and bone-derived scaffolds in a dynamic environment enhances osteochondral reconstruction. J Biol Macromol. 2024 Dec; 283(Pt 4): 137892.

5. Song KD*, et al. A Gelatin/Polyacrylamide-Based Hydrogel for Smart Drug Release Monitoring and Radiation-Induced Wound Repair in Breast Cancer. J Biol Macromol. 2024 Dec; 283(Pt 4): 137845.

6. Song KD*, et al. A capsule-based scaffold incorporating decellularized extracellular matrix and curcumin for islet beta cell therapy in type 1 diabetes mellitus. Biofabrication. 2024 Sep 10. doi: 10.1088/1758-5090/ad7907.

7. Song KD*, et al. Molecular secondary recombination for pitch-derived carbon microsphere toward ultra-high sodium storage. Carbon, 2024, 226: 119200.

8. Song KD*, et al. S/O co-doped honeycomb-like porous carbon nanosheets with ultra-high edge defects for high-performance sodium storage. Carbon, 2024, 219: 118825.

9. Song KD*, et al. Caffeic acid-grafted chitosan/sodium alginate/nanoclay-based multifunctional 3D-printed hybrid scaffolds for local drug release therapy after breast cancer surgery. Carbohydr Polym. 2024 Jan 15; 324: 121441.

10. Song KD*, et al. Electromagnetic field-mediated chitosan/gelatin/nano-hydroxyapatite and bone-derived scaffolds regulate the osteoblastic and chondrogenic phenotypes of adipose-derived stem cells to construct osteochondral tissue engineering niche in vitro. Int J Biol Macromol. 2023 Dec 19; 258(Pt 1):128829.

11. Song KD*, et al. Functional materials of 3D bioprinting for wound dressings and skin tissue engineering applications: A review. Int J Bioprint. 2023 Mar 18; 9(5): 757.

12. Song KD*, et al. A decellularized lung extracellular matrix/chondroitin sulfate/gelatin/chitosan-based 3D culture system shapes breast cancer lung metastasis. Biomater Adv. 2023 Sep; 152: 213500. 

13. Song KD*, et al. A biocompatible double-crosslinked gelatin/ sodium alginate/dopamine/ quaterniazed chitosan hydrogel for wound dressings based on 3D bioprinting technology. Int J Bioprint. 2023 Feb 20; 9(2): 689.

14. Song KD*, et al. 3D bioprinting of dECM/Gel/QCS/nHAp hybrid scaffolds laden with mesenchymal stem cell-derived exosomes to improve angiogenesis and osteogenesis. Biofabrication. 2023 Feb 9; 15(2). 024103.

15. Song KD*, et al. Curcumin nanoparticles combined with 3D printed bionic tumor models for breast cancer treatment. Biofabrication. 2023(2022 Dec 8); 15(1): 014105.

16. Song KD*, et al. A 3D bioprinted tumor model fabricated with gelatin/sodium alginate/decellularized extracellular matrix bioink. Int J Bioprint. 2023(2022 Oct 28); 9(1): 630.

17. Song KD*, et al. A 3D bioprinted decellularized extracellular matrix/gelatin/ quaternized chitosan scaffold assembling with poly (ionic liquid) s for skin tissue engineering. Int J Biol Macromol. 2022 Nov 1; 220: 1253-1266. 

18. Song KD*, et al. Gelatin/sodium alginate hydrogel-coated decellularized porcine coronary artery to construct bilayer tissue engineered blood vessels. Int J Biol Macromol. 2022 Jun 1; 209(Pt B): 2070-2083.

19. Song KD*, et al. Dynamic process enhancement on chitosan/gelatin/nano-hydroxyapatite-bone derived multilayer scaffold for osteochondral tissue repair. Biomater Adv. 2022 Feb; 133: 112662.

20. Song KD*, et al. A biological functional hybrid scaffold based on decellularized extracellular matrix/gelatin/chitosan with high biocompatibility and antibacterial activity for skin tissue engineering. Int J Biol Macromol. 2021 Sep 30; 187: 840-849.

21. Song KD*, et al. Evaluation of anti-tumor effects of crocin on a novel 3D tissue-engineered tumor model based on sodium alginate/gelatin microbead. Int J Biol Macromol. 2021 Mar 31; 174: 339-351.

22. Song KD*, et al. Evaluation of inhibitory effects of geniposide on a tumor model of human breast cancer based on 3D printed Cs/Gel hybrid scaffold. Mater Sci Eng C Mater Biol Appl. 2021 Feb; 119: 111509. 

23. Song KD*, et al. Screening ionic liquids for dissolving a melamine formaldehyde resin prepolymer to fabricate flame-retardant fibers. ACS Sustainable Chemistry & Engineering, 2020, 8(49): 18314-18323.

24. Song KD*, et al. Toxicological evaluation of ionic liquid in a biological functional tissue construct model based on nano-hydroxyapatite/chitosan/gelatin hybrid scaffolds. Int J Biol Macromol. 2020 May 5; 158: 800-810.

25. Song KD*, et al. Engineering gelatin-based alginate/carbon nanotubes blend bioink for direct 3D printing of vessel constructs. Int J Biol Macromol. 2020 Feb 15; 145: 262-271.

26. Song KD*, et al. Characterization and anti-tumor bioactivity of astragalus polysaccharides by immunomodulation. Int J Biol Macromol. 2020 Feb 15; 145: 985-997.

27. Song KD*, et al. Anti-tumor potential of astragalus polysaccharides on breast cancer cell line mediated by macrophage activation. Mater Sci Eng C Mater Biol Appl. 2019 May; 98: 685-695. 

28. Song KD*, et al. Multiple comparisons of three different sources of biomaterials in the application of tumor tissue engineering in vitro and in vivo. Int J Biol Macromol. 2019 Jun 1; 130: 166-176.

29. Song KD*, et al. Effects of concentration variation on the physical properties of alginate-based substrates and cell behavior in culture. Int J Biol Macromol. 2019 May 1; 128: 184-195.

30. Song KD*, et al. A novel tissue-engineered 3D tumor model for anti-cancer drug discovery. Biofabrication. 2018 Oct 30; 11(1):015004. 

 

2003.9 -- 2006.7
大连理工大学       化学工程       博士

2001.9 -- 2003.7
大连理工大学       化学工程       硕士

2006.8 -- 至今

大连理工大学

2020.1 -- 2020.12

国际SCI检索刊物Curr Cancer Drug Tar(IF=2.912)编委(国际SCI/EI刊物编辑/编委)

2020.1 -- 2020.12

国际SCI检索刊物Curr Stem Cell Res Ther(IF=2.614)编委(国际SCI/EI刊物编辑/编委)

2020.1 -- 2020.12

国际SCI检索刊物Curr Pharm Biotechnol(IF=2.097)编委(国际SCI/EI刊物编辑/编委)