王天笑
Assistant Professor Supervisor of Master's Candidates
Gender:Male
Alma Mater:吉林大学
Degree:Doctoral Degree
School/Department:化工学院
Discipline:Chemical Engineering
E-Mail:
Hits:
Date:2026-01-08
Indexed by:Journal Article
Date of Publication:2024-02-09
Journal:Frontiers in Chemistry
Included Journals:SCI
Volume:12
ISSN:2296-2646
Key Words:dental materials, polymethyl methacrylate, polyethylene oxide, fluoride ion release, polymer blend
Abstract:Introduction: Polymethyl methacrylate is a polymer commonly used in clinical dentistry, including denture bases, occlusal splints and orthodontic retainers.
Methods: To augment the polymethyl methacrylate-based dental appliances in counteracting dental caries, we designed a polymer blend film composed of polymethyl methacrylate and polyethylene oxide by solution casting and added sodium fluoride.
Results: Polyethylene oxide facilitated the dispersion of sodium fluoride, decreased the surface average roughness, and positively influenced the hydrophilicity of the films. The blend film made of polymethyl methacrylate, polyethylene oxide and NaF with a mass ratio of 10: 1: 0.3 showed sustained release of fluoride ions and acceptable cytotoxicity. Antibacterial activity of all the films to Streptococcus mutans was negligible.
Discussion: This study demonstrated that the polymer blends of polyethylene oxide and polymethyl methacrylate could realize the relatively steady release of fluoride ions with high biocompatibility. This strategy has promising potential to endow dental appliances with anti-cariogenicity.
DOI Number:10.3389/fchem.2024.1356029
Impact Factor:4.0
Tianxiao Wang, the assistant professor, obtained his doctoral degree from Jilin University, China in 2023. Then, he worked as a postdoc at Umeå University, Sweden from 2023 to 2025. His research interests include anti-fouling coating, microbiological influenced corrosion and biomedical materials especially magnesium alloy based biomaterials. He have published over 10 papers on journals including Journal of Magnesium Alloys, Progess of Organic Coatings and Ceramisc International and so on. The students who are interested in corrosion resistant coatings and biomaterials are welcomed.
