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发布期刊链接：https://www.sciencedirect.com/science/article/pii/S0300944023000139?via%3Dihub

论文类型：期刊论文

发表时间：2023-01-27

发表刊物：Progress in Organic Coatings

收录刊物：SCI

卷号：177

ISSN号：0300-9440

关键字：Magnesium alloy, Composite coating, Corrosion resistance, Biocompatibility, Bone tissue engineering

摘要：As a potential new metal biomaterial implant, the problem of fast degradation of magnesium (Mg) alloy and the resulting hydrogen release and local alkalinization need to be solved urgently. To this end, a double-layer dicalcium phosphate dihydrate (DCPD) sandwiched siloxane composite coating was prepared on Mg alloy via chemical conversion, immersion treatment and biomimetic deposition methods. The morphologies and compositions of the samples were systematically analyzed, and the corrosion resistance, as well as the biocompatibility, was specifically explored. The electrochemical test result evidenced that the corrosion current density of the composite coated sample was 3.0 × 10−8 A/cm2, which was much smaller than that of Mg alloy (1.4 × 10−5 A/cm2). The immersion experiment showed that the coating provided continuous protection to the sample. The hydrogen evolution of the optimal coating was only 1/9 of that of Mg alloy, and the coated sample had good biomineralization ability. The coated samples also showed good biocompatibility in cell experiments (cell viability ≥116.5 %). This study proposes a novel idea for the construction of surface coatings of biomedical Mg alloys for bone tissue engineering.

DOI码：10.1016/j.porgcoat.2023.107417

影响因子：7.3