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发布期刊链接：https://pubs.acs.org/doi/10.1021/acs.langmuir.0c02442

论文类型：期刊论文

发表时间：2020-11-10

发表刊物：Langmuir

收录刊物：SCI

卷号：36

期号：46

页面范围：13937-13948

ISSN号：0743-7463

关键字：Alloys, Coating materials, Composites, Electrochemistry, Oxidation

摘要：The excellent biocompatibility of calcium phosphate (CaP) coatings makes them widely used in magnesium (Mg) alloy orthopedic implant materials. However, the porous morphology of CaP coatings limits their corrosion resistance. A cupric oxide (CuO) doped titania (TiO2) sol–gel coating is prepared on a porous hydroxyapatite (HA) coating. According to electrochemical test results, the HA/CuO–TiO2 coating obtains a current density of 6 × 10–4 mA/cm2, lower than that of the Mg alloy (2.6 × 10–2 mA/cm2). The hydrogen evaluation of the HA/CuO–TiO2 coating is only 1/12 that of the Mg alloy after immersion for 7 days. In addition, the HA/CuO–TiO2 coating has an antibacterial rate of 99.5 ± 0.4% against Staphylococcus aureus, significantly higher than that of the HA coating (19.8 ± 0.3%) and HTC0 coating (38.4 ± 0.5%). The CuO doped composite coating has no adverse effect or cytotoxicity on cell proliferation (cell viability ≥79.6%). Hence, the HA/CuO–TiO2 composite coating is useful for enhancing the corrosion resistance and antibacterial properties of Mg alloys while ensuring cytocompatibility. The HA/CuO–TiO2 coated AZ60 Mg alloy can meet the requirements of clinical application.

DOI码：10.1021/acs.langmuir.0c02442

影响因子：3.9