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王紫千
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副教授
博士生导师
硕士生导师
- 性别：男
- 出生日期：1990-01-30
- 毕业院校：大连理工大学
- 学位：博士
- 所在单位：医学部
- 学科：化学生物学
- 办公地点：大连理工大学西部校区化工综合楼C523
- 电子邮箱：Wangziqian@dlut.edu.cn
访问量：
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[1] 王哲明, 黎怡同, 王紫千, 张志超.基于疏水标签的Bcl-2/Mcl-1蛋白泛素化降解剂[J],药学学报,2024,59(11):2990-2996
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[2] 蒋茂军, 王子涵, 王思尧, 殷方奎, 李鑫, 王哲明, 黎怡同, 张弘, Zhang, Yanxin, Lu, Shaohua, Xu, Guanghong, 宋婷, 王紫千, 张志超, Song, Yang, Hu, Zhiyuan, Wang, Yuying, Ziqian, Zhang, Zhichao.Discovery of Biphenyl Derivatives to Target Hsp70-Bim Protein-Protein Interaction in Chronic Myeloid[J],JOURNAL OF MEDICINAL CHEMISTRY,2024,67(14):12068-12084
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[3] 殷方奎, 刘晶晶, 唐尧, 宋婷, Liu, Jingjing, 张弘, Tang, Yao, 张志超, Song, Ting, 王紫千, Zhang, Hong, Zhichao, Zhang.Hsp70-Bim incoherent feedforward loop contributes to cell-fate heterogeneity and fractional killing.[J],British journal of pharmacology,2023
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[4] He, Guangli, 杜健军, 孙文, 贺毛毛, 王然, 吕洋, Du, Jianjun, 樊江莉, 彭孝军, Sun, Wen, Wang, Ran, 李学召, Hu, Hanze, Dongsheng, 王紫千, Lu, Yang, Xu, Ning, Li, Xuezhao, Sun.A Near-Infrared Light-Activated Photocage Based on a Ruthenium Complex for Cancer Phototherapy.[J],Angewandte Chemie (International ed. in English),2023,62(24):e202218768
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[5] Song, Ting, 宋婷, 殷方奎, 郭亚飞, 张志超, 王紫千, Zhang, Hong, Liu, Peng, Tang, Yao, Zhichao, Zhang.Hsp70-Bim interaction facilitates mitophagy by recruiting parkin and TOMM20 into a complex.[J],Cellular & molecular biology letters,2023,28(1):46
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[6] Liu, Jingjing, 殷方奎, 宋婷, 张志超, 王紫千, Song, Ting, Zhang, Zhichao, Zhang.An updated patent review of Mcl-1 inhibitors (2020-2022).[J],Expert opinion on therapeutic patents,2023,33(5):371-383
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[7] 宋婷, 胡治远, Zhang, Hong, Zhao, Qicheng, 王紫千, Song, Yang, 张志超, Ting, Zhang, Zhichao.Small molecule inhibitor targeting the Hsp70-Bim protein-protein interaction in estrogen receptor-po[J],Breast cancer research : BCR,2024,26(1):33
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[8] Wang, Yuying, 蒋茂军, 袁琳杰, Hu, Zhiyuan, Zhang, Yanxin, 王紫千, 宋婷, 张志超, Song, Ting, Zhang, Zhichao.Yeast Bxi1/Ybh3 mediates conserved mitophagy and apoptosis in yeast and mammalian cells: convergence[J],Biological chemistry,2024
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[9] Li, Xin, 王钰莹, 蒋茂军, 殷方奎, 袁琳杰, 刘晶晶, 王兴钰, 张弘, 张志超, 王紫千, Wang, Ziqian, Zhang, Zhichao.Exploring the binding mechanism of a small molecular Hsp70-Bim PPI inhibitor through molecular dynam[J],Journal of molecular modeling,2024,30(3):71
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[10] 袁琳杰, 王钰莹, Wang, Yuying, Margulis, B. A., 宋婷, 王紫千, 张志超, Song, Ting.Ectopic BH3-Only Protein Bim Associates with Hsp70 to Regulate Yeast Mitophagy.[J],Doklady. Biochemistry and biophysics,2023,512(1):292-299
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[11] 王紫千, 袁琳杰, 胡治远, 高岐双, 蒋茂军, 殷方奎, 张弘, Liu, Jingjing, 宋婷, Lu, Shaohua, Xu, Guanghong, 张志超, Li, Xin, Song, Yang, Wang, Yuying, Zhang, Zhichao.Exploiting the "Hot-Spots" of Hsp70-Bim Protein-Protein Interaction to Optimize the 1-Oxo-1H-phenale[J],Journal of medicinal chemistry,2023
