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论文类型：期刊论文

发表时间：2012-04-01

发表刊物：IEEE TRANSACTIONS ON PLASMA SCIENCE

收录刊物：SCIE、EI、Scopus

卷号：40

期号：4

页面范围：1098-1102

ISSN号：0093-3813

关键字：Atmospheric pressure plasma; biomedical application; glowlike discharge; optical emission spectroscopy (OES); plasma brush; scanning electron microscope (SEM); sterilization; survival efficiency

摘要：It remains a challenge to generate the uniform and large-area cold plasma at atmospheric pressure. In this paper, we report a method to generate a reliable and homogeneous brush-shaped plasma plume running at atmospheric pressure. The plasma brush (110 mm in length and 10 mm in width) is mainly composed of well-aligned and hollow optical fibers. Current-voltage measurements indicate that the brush-shaped plasma plume consists of glowlike pulsed discharge with their pulsewidths of several microseconds. The generation of the He/O-2 glowlike discharge is further proved by the uniform distribution of O atoms along the transverse location of the plasma brush. This brush-shaped plasma plume is used for the application in the plasma inactivation of Candida albicans cells. About 97% of Candida albicans cells with a population of 10(5) spores are killed when exposed to the O-2/He (volume ratio: 5/95) brush-shaped plasma plume for 150 s. Analysis indicates that plasma-activated species, such as O radicals, may play a crucial role in killing the resistant Candida albicans cells.