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论文类型： 期刊论文

发表时间： 2017-06-14

发表刊物： TETRAHEDRON LETTERS

收录刊物： SCIE、Scopus

卷号： 58

期号： 24

页面范围： 2351-2354

ISSN号： 0040-4039

关键字： Hydrazine; Hydrazinolysis; Cinnamoyl; pi-pi conjugate

摘要： Herein we discovered that a Nile Red-based probe with a cinnamoyl unit was highly selective and sensitive to N2H4. Hydrazinolysis by N2H4 would release a hydroxyl substituted Nile Red and result in remarkable fluorescence quench. Importantly, Cys/Hcy would not interrupt the N2H4 recognition. This is because, for this probe, the combination of the pi-pi conjugate system can stabilize the ethylene union, which results in the nucleophilic addition of the thiol group of Cys/Hcy becomes non -effective. (C) 2017 Elsevier Ltd. All rights reserved.