Indexed by:Journal Papers

Date of Publication:2020-02-01

Journal:COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Included Journals:PubMed、SCIE、EI

Volume:184

Page Number:105120

ISSN No.:0169-2607

Key Words:Electrocardiogram (ECG); Myocardial infarction (MI); Dual-Q tunable Q-factor wavelet transformation (Dual-Q TQWT); Discrete wavelet packet transform (DWPT); Multilinear principal component analysis (MPCA)

Abstract:Background and objective: It is challenging to conduct real-time identification of myocardial infarction (MI) due to artifact corruption and high dimensionality of multi-lead electrocardiogram (ECG). In the present study, we proposed an automated single-beat MI detection and localization system using dual-Q tunable Q-factor wavelet transformation (Dual-Q TQWT) denoising algorithm.
   Methods: After denoising and segmentation of ECG, a fourth-order wavelet tensor (leads x subbands x samples x beats) was constructed based on the discrete wavelet packet transform (DWPT), to represent the features considering the information of inter-beat, intra-beat, inter-frequency, and inter-lead. To reduce the tensor dimension and preserve the intrinsic information, the multilinear principal component analysis (MPCA) was employed. Afterward, 84 discriminate features were fed into a classifier of bootstrap-aggregated decision trees (Treebagger). A total of 78 healthy and 328 MI (6 types) records including 57557 beats were chosen from PTB diagnostic ECG database for evaluation.
   Results: The validation results demonstrated that our proposed MI detection and localization system embedded with Dual-Q TQWT and wavelet packet tensor decomposition outperformed commonly used discrete wavelet transform (DWT), empirical mode decomposition (EMD) denoising methods and vector-based PCA method. With the Treebagger classifier, we obtained an accuracy of 99.98% in beat level and an accuracy of 97.46% in record level training/testing for MI detection. We also achieved an accuracy of 99.87% in beat level and an accuracy of 90.39% in record level for MI localization.
   Conclusion: Altogether, the automated system brings potential improvement in automated detection and localization of MI in clinical practice. (C) 2019 Elsevier B.V. All rights reserved.