张志超

个人信息Personal Information

教授

博士生导师

硕士生导师

性别：女

毕业院校：大连理工大学

学位：博士

所在单位：医学部

学科：化学生物学. 药理学. 细胞生物学

办公地点：Chemical complex building,D513

联系方式：

电子邮箱：

扫描关注

同专业博导同专业硕导个人学术主页

当前位置：中文主页 >> 科学研究

研究领域

1. Bcl-2 inhibitors as target anti-tumor drug

2. Bcl-2 pathway

论文成果 更多>>

张志超.Wang, Yuanyuan,Song, Ting,Gao, Jin,Wu, Guiye,Zhang, Jing,Qian, Xuhong.DNA Double Helix Unwinding Triggers Transcription Block-Dependent Apoptosis: A Semiquantitative Probe of the Response of ATM, RNAPII, and p53 to Two DNA Intercalators[J],CHEMICAL RESEARCH IN TOXICOLOGY,2021,22(3):483-491
王紫千.宋婷,张志超.Targeting the allosteric pathway that interconnect the core-functional scaffold and the distal phosphorylation sites for specific dephosphorylation of Bcl-2.[J],Journal of medicinal chemistry,2021,63(1111):13733-13744
张志超.张肖冬,王紫千.A “three-in-one” multi-functional probe for Bcl-2/Mcl-1 profiling and visualizing in situ.[J],ChemBioChem,2021,22:326-329
Zhu Junjie.Song Ting,Guo Yafei,Ji Tong,Zhang Zhichao,Wang Ziqian,Guo Zongwei,Zhang Xiaodong.Structure-based design, synthesis, and evaluation of Bcl-2/Mcl-1 dual inhibitors[J],Archiv der Pharmazie,2020,353(5):e2000005
张志超.Affinity-based probe reveal Bim negatively regulates the chaperone functions of Hsp70, a non-Bcl-2 BH3 receptor..[A],2019,(13 Supplement): 79:2754-
郭宗伟.刘朋,张民行,张肖冬,张志超,宋婷,薛祖光.Using CETSA assay and a mathematical mode lto reveal dual Bcl-2/Mcl-1 inhibition and on-target mechanism for ABT-199 and S1[J],European Journal of Pharmaceutical Sciences,2019,142(15)

专利 更多>>

著作成果 更多>>

陈宏博,张志超,李忠义,生物有机化学,大连理工大学出版社,2019

科研项目 更多>>