Title of Paper:Chiral catalyst-directed site-selective functionalization of hydroxyl groups in carbohydrates

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Date of Publication:2017-01-01

Journal:JOURNAL OF CARBOHYDRATE CHEMISTRY

Included Journals:SCIE

Volume:36

Issue:4-6

Page Number:143-161

ISSN No.:0732-8303

Key Words:Site-selectivity; chiral catalyst; functionalization; hydroxyl groups

Abstract:Carbohydrates perform essential roles in living organisms. Recently, a series of breakthroughs emerged in chiral catalyst-directed site-selective functionalization of carbohydrates. In this review site-selective functionalization of cis-diols, trans-diols and others mediated by chiral catalysts was discussed. The reaction types covered are mainly acylation, acetalization, glycosidation, thiocarbonylation, silylation, phosphorylation, sulfonylation, and so on. Some important site-selective methodologies used in the synthesis of saccharides are also elaborated.