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论文类型： 期刊论文

发表时间： 2006-07-01

发表刊物： JOURNAL OF BIOMECHANICS

收录刊物： SCIE、EI、PubMed

卷号： 39

期号： 1

页面范围： 21-32

ISSN号： 0021-9290

关键字： stent; finite element method; design optimization; dogboning; foreshortening

摘要： The percutaneous transluminal coronary angioplasty (PTCA) assisted with stenting technique has become a primary therapy to coronary heart disease. In practice, the structure conditions of both ends of stent/balloon system influence a stent's instantaneous expansion behavior. The transitory nonuniform expansion, the so-called dogboning, of stent/balloon system is one of the main reasons to induce the acute vascular injury at the two edges of a stent. This kind of vascular injury has a close relationship with the in-stent restenosis. In the present paper, the finite element method (FEM) was applied to simulate the transient expansion process of stent/balloon system with different stent structure and balloon length under the internal pressure. And two types of stent and six collocations of stent and balloon were modeled. Modeling results showed that the dogboning phenomenon can be eliminated by improving geometry of a stent or/and varying the length of balloon over stent. The above modeled results were further confirmed by following in situ observation. (c) 2004 Elsevier Ltd. All rights reserved.