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论文类型：会议论文
发表时间：2009-12-15
收录刊物：EI、CPCI-S、Scopus
页面范围：6213-6217
摘要：In this paper, the nonlinear dynamical system of batch fermentation is investigated in the bioconversion of glycerol to 1,3-propanediol(1,3-PD) by Klebsiella pneumoniae. Taking account of the kinetic behavior and experimental results in the batch cultures, we propose a two-stage dynamical system to formulate the fermentation process. Then some properties of the proposed system are proved. In view of the big errors between observations and numerical simulation results, we subsequently establish a parameter identification model to identify parameters in the system. The identifiability of the model is also discussed. Finally, in order to find the optimal parameters of the identification model, an improved simulated annealing algorithm combined with Hook-Jeeves local search is constructed. Numerical results show that the two-stage system can describe the factual fermentation better and the optimization algorithm is valid.