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肺炎克雷伯杆菌中CRISPR的基因组分析与基于CRISPR的噬菌体抗性菌株的构建策略

Release Time:2019-03-13  Hits:

Indexed by: Conference Paper

Date of Publication: 2015-01-01

Page Number: 4-4

Abstract: 肺炎克雷伯杆菌因能高效的利用廉价的碳源(菊芋、糖蜜、粗甘油等)生产2,-3-丁二醇,1,3-丙二醇等高附加值的化学品而受到广泛的关注。本文利用已公开的肺炎克雷伯杆菌全基因组信息对CRISPR/Cas系统进行了鉴定与分析。并提出了两种基于CRISPR的噬菌体抗性菌株的构建策略。

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