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微生物法生产1,3-丙二醇不同分离工艺的生产成本分析

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Indexed by:期刊论文

Date of Publication:2022-06-30

Journal:化工进展

Volume:31

Issue:1

Page Number:35-40

ISSN No.:1000-6613

Abstract:The preliminary design for the bioconversion of 1,3-propanediol from
   glycerol with annual production capacity of 1000 tons was achieved by
   three separation processes operated sequentially,which were an aqueous
   two-phase extraction,an alcohol precipitation and an electrodialysis.The
   process simulation software,ProⅡ,was used to simulate the three
   downstream processes.Based on energy and material balance,the raw
   material,utilities and equipments costs of these three processes were
   calculated.The cost analysis indicated that the total costs of alcohol
   precipitation,aqueous two-phase extraction and electrodialysis were
   14793,14201 and 14345(RMB/t),respectively.The economic sensitivity
   analysis showed that the price of glycerol was the key factor
   influencing the unit costs.The increasing of the concentration and yield
   of 1,3-propanediol will help to reduce production costs and improve
   process economic efficiency.

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