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微生物连续发酵建模及胞内动力学参数辨识

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Indexed by:期刊论文

Date of Publication:2022-06-30

Journal:大连理工大学学报

Issue:3

Page Number:458-463

ISSN No.:1000-8608

Abstract:A dynamical system concerning intracellular substances and transport patterns was proposed to describe glycerol bioconversion to 1, 3-propanediol in continuous fermentation process. Some properties of the system were subsequently discussed. Taking the error between the computational values and experimental data as the cost function, a parameter identification model to identify the intracellular kinetic parameters was established. The existence of the optimal parameters in the parameter identification model was also proved. Finally, an improved particle swarm optimization was constructed to solve the above parameter identification model. Numerical results show that the mean relative error is cut down by 20.635%, and the proposed algorithm has higher global convergence compared with other optimization algorithms.

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