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Isolation and characterization of two new phenolic acids from cultured cells of Saussurea involucrata

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Indexed by:期刊论文

Date of Publication:2014-02-01

Journal:PHYTOCHEMISTRY LETTERS

Included Journals:SCIE、Scopus

Volume:7

Issue:1

Page Number:133-136

ISSN No.:1874-3900

Key Words:Cultured cells of Saussurea involucrata; Phenolic acid; Free radical scavenging activity

Abstract:Two new phenolic acids, 1, 5-O-dicaffeoyl-3-O-(4-maloyl)-quinic acid (1) and 3, 5-di-O-caffeoyl-1-O-(2-O-caffeoyl-4-maloyl)-quinic acid (2), were isolated from cultured cells of Saussurea involucrata. Their structures were elucidated using 2D NMR spectroscopy and MS. Further in vitro bioactive investigations demonstrated that 3, 5-di-O-caffeoyl-1-O-(2-O-caffeoyl-4-maloyl)-quinic acid (2) had significant scavenging activities against radicals 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) and 2, 20-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS). (C) 2013 Published by Elsevier B.V. on behalf of Phytochemical Society of Europe.

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