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Indexed by:期刊论文

Date of Publication:2019-10-01

Journal:SENSORS AND ACTUATORS B-CHEMICAL

Included Journals:SCIE、EI

Volume:296

ISSN No.:0925-4005

Key Words:Plasmonic probe; Adenosine detection; Gold nanoparticle; Eyedropper function; Colorimetric assay

Abstract:Adenosine, as an endogenous molecule in organisms, plays an essential role in biological processes. Here, a plasmonic probe, creatinine-Ag+/gold nanoparticle (AuNPs), is assembled for adenosine detection based on synergistic coordination on AuNPs. The A(650 nm/520 nm) values of AuNPs system change linearly with adenosine concentration over a range of 1.0-5.0 mu M and the detection limits reached 45 nM. The adenosine detection is realized within 4 min. Furthermore, the quantitative detection of adenosine is realized by eyedropper (a function in Microsoft's PowerPoint) for analyzing RGB value changes of colorimetric assay. Therefore, this sensor can provide accurate and rapid assay of adenosine in patients' serum sample without complicated instrumentations.