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Indexed by:期刊论文

Date of Publication:2006-07-05

Journal:JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

Included Journals:SCIE、Scopus

Volume:181

Issue:1

Page Number:79-85

ISSN No.:1010-6030

Key Words:near-infrared cyanine dye; photostability; fluorescence quantum yield; photobleaching; fluorescence labeling

Abstract:Novel near-infrared (NIR) 3H-indocyanine dyes with different N-substituents were synthesized and tested to make clear the relationship between photophysical properties and structures and develop potential NIR cyanine dyes with high photostability for fluorescent imaging technology. The electron-withdrawing ability of the substituents on N-position of 3H-indolenine strongly affects the photostabilities of the NIR cyanine dyes and introducing of the electron-donating groups is favorable to obtain NIR cyanine dyes with improved photochemical stability. (c) 2005 Elsevier B.V. All rights reserved.