个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职:Director, State Key laboratory of Fine Chemicals
其他任职:精细化工国家重点实验室主任、国务院学科评议组成员
性别:男
毕业院校:大连理工大学
学位:博士
所在单位:化工学院
学科:应用化学. 精细化工. 化学生物学
办公地点:大连理工大学精细化工国家重点实验室
西部校区化工实验楼F-202#
http://peng-group.dlut.edu.cn/
联系方式:大连理工大学精细化工国家重点实验室 西部校区化工实验楼F-202 辽宁省大连市高新区凌工路2号,大连116024 Tel: 0411-84986306; Fax: 0411-84986292;课题组网址:http://peng-group.dlut.edu.cn/
电子邮箱:pengxj@dlut.edu.cn
Lighting-up breast cancer cells by a near-infrared fluorescent probe based on KIAA1363 enzyme-targeting
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论文类型:期刊论文
发表时间:2017-05-01
发表刊物:CHEMICAL COMMUNICATIONS
收录刊物:SCIE、PubMed
卷号:53
期号:35
页面范围:4857-4860
ISSN号:1359-7345
摘要:The first NIR KIAA1363-targeting probe, NB-AX, specifically and instantly featured an "off-on'' switch upon gradual addition of KIAA1363 over all kinds of other biomolecules, and its detection limit was initially calculated to be 0.58 mu g mL(-1) (3d/k). The probe was also able to be used in ultrafast distinguishing of breast cancer cells from normal cells in fluorescence imaging and applied in tissue imaging and tumor imaging in vivo.