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个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职：Director, State Key laboratory of Fine Chemicals
其他任职：精细化工国家重点实验室主任、国务院学科评议组成员
性别：男
毕业院校：大连理工大学
学位：博士
所在单位：化工学院
学科：应用化学. 精细化工. 化学生物学
办公地点：大连理工大学精细化工国家重点实验室
西部校区化工实验楼F-202#
http://peng-group.dlut.edu.cn/
联系方式：大连理工大学精细化工国家重点实验室 西部校区化工实验楼F-202 辽宁省大连市高新区凌工路2号，大连116024 Tel: 0411-84986306; Fax: 0411-84986292；课题组网址：http://peng-group.dlut.edu.cn/
电子邮箱：pengxj@dlut.edu.cn
A NIR fluorescent probe: imaging endogenous hydrogen peroxide during an autophagy process induced by rapamycin
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论文类型：期刊论文
发表时间：2016-01-01
发表刊物：JOURNAL OF MATERIALS CHEMISTRY B
收录刊物：SCIE、EI
卷号：4
期号：46
页面范围：7363-7367
ISSN号：2050-750X
摘要：In this work, a near-infrared probe (Cy-B) with high sensitivity, and good specificity as well as photo-stability has been developed for monitoring both exogenous and endogenous H2O2 in living cells. To the best of our knowledge, it was applied successfully for the first time to monitor spontaneous hydrogen peroxide in an autophagy process induced by the stimulation of rapamycin. The mice imaging experiments indicate that the probe has a good potential to be employed in the imaging of living biological systems.