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个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职：中国化学会创始会士、常务理事，中国化工学会会士
性别：男
毕业院校：大连理工大学
学位：博士
所在单位：化工学院
学科：应用化学. 精细化工. 化学生物学
办公地点：大连理工大学西部校区知顺楼F-202#
http://peng-group.dlut.edu.cn/
联系方式：大连理工大学西部校区知顺楼F-202 辽宁省大连市高新区凌工路2号，大连116024 课题组网址：http://peng-group.dlut.edu.cn/ E-mail: pengxj@dlut.edu.cn
电子邮箱：pengxj@dlut.edu.cn
Fluorescent Nanosensors Based on Fluorescence Resonance Energy Transfer (FRET)
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论文类型：期刊论文
发表时间：2013-08-21
发表刊物：INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
收录刊物：SCIE、EI、Scopus
卷号：52
期号：33
页面范围：11228-11245
ISSN号：0888-5885
摘要：Fluorescence resonance energy transfer (FRET) has been widely used as a spectroscopic technique in various areas such as structural elucidation of biological molecules and their interactions, in vitro assays, in vivo monitoring in cellular research, nucleic acid analysis, signal transduction, light harvesting, and metallic nanomaterials. Meanwhile, based on the mechanism of FRET, a series of FRET nanomaterials systems have been recently developed as novel chemical sensors and biosensors. Compared with those based on small molecules traditional FRET systems, the surface chemistry of nanomaterial has encouraged the development of multiple probes based on linked recognition molecules such as peptides, nucleic acids, or small-molecule ligands. This critical review highlights the design and the applications of sensitive and selective ratiometric nanoprobes based on FRET. We focus on the benefits and limitations of nano-FRET systems and their applications as chemical sensors and biosensors.