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个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职:中国化学会创始会士、常务理事,中国化工学会会士
性别:男
毕业院校:大连理工大学
学位:博士
所在单位:化工学院
学科:应用化学. 精细化工. 化学生物学
办公地点:大连理工大学西部校区知顺楼F-202#
http://peng-group.dlut.edu.cn/
联系方式:大连理工大学西部校区知顺楼F-202 辽宁省大连市高新区凌工路2号,大连116024 课题组网址:http://peng-group.dlut.edu.cn/ E-mail: pengxj@dlut.edu.cn
电子邮箱:pengxj@dlut.edu.cn
Spectroscopic Techniques Study on the Quenching Mechanism of Cytochrome B5 Affected by Cu(II)
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论文类型:期刊论文
发表时间:2013-04-01
发表刊物:ASIAN JOURNAL OF CHEMISTRY
收录刊物:SCIE、Scopus
卷号:25
期号:4
页面范围:2054-2058
ISSN号:0970-7077
关键字:Cytochrome B5; Quenching mechanism; Spectrosciopic techniques
摘要:The interaction between Cu2+ and cytochrome b5 (cytb5) has been investigated by multi-spectroscopic techniques. The results show that Cu2+ could interact with cytochrome b5 and induce fluorescence of the latter to be quenched. The quenching mechanism is dominated by dynamic quenching. Synchronous fluorescence and circular dichroism spectra demonstrate that Cu2+ could also influence the microcircumatance of aromatic amino residues and secondary structure of the protein.