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个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职:中国化学会创始会士、常务理事,中国化工学会会士
性别:男
毕业院校:大连理工大学
学位:博士
所在单位:化工学院
学科:应用化学. 精细化工. 化学生物学
办公地点:大连理工大学西部校区知顺楼F-202#
http://peng-group.dlut.edu.cn/
联系方式:大连理工大学西部校区知顺楼F-202 辽宁省大连市高新区凌工路2号,大连116024 课题组网址:http://peng-group.dlut.edu.cn/ E-mail: pengxj@dlut.edu.cn
电子邮箱:pengxj@dlut.edu.cn
Ratiometric Detection of Viscosity Using a Two-Photon Fluorescent Sensor
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论文类型:期刊论文
发表时间:2013-01-01
发表刊物:CHEMISTRY-A EUROPEAN JOURNAL
收录刊物:SCIE、EI、PubMed、Scopus
卷号:19
期号:5
页面范围:1548-1553
ISSN号:0947-6539
关键字:cells; fluorescence; sensors; two-photon microscopy; viscosity
摘要:In the thick of it: A carbazole-based cyanine derivative has been used as a ratiometric fluorescent sensor to detect mitochondrial viscosities over the range 1-950 cP within live cells and living tissues by using two-photon microscopy. Its success is based on the fast- and low-barrier rotation around its methine bond (see figure) and the huge increase of the fluorescence quantum yield (QY) from the loss of mobility in viscous media. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.