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个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职：中国化学会创始会士、常务理事，中国化工学会会士
性别：男
毕业院校：大连理工大学
学位：博士
所在单位：化工学院
学科：应用化学. 精细化工. 化学生物学
办公地点：大连理工大学西部校区知顺楼F-202#
http://peng-group.dlut.edu.cn/
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Preparation and folic acid conjugation of fluorescent polymer nanoparticles for cancer cell targeting
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论文类型：期刊论文
发表时间：2012-08-21
发表刊物：JOURNAL OF MATERIALS CHEMISTRY
收录刊物：Scopus、EI、SCIE
卷号：22
期号：31
页面范围：16078-16083
ISSN号：0959-9428
摘要：Fluorescent polymer nanoparticles have been prepared by emulsion polymerization with a polymerisable anthrapyridone dye. This connects covalently to the polymer chains, preventing dye leakage. Amino groups were introduced into the nanoparticles by grafting with PEI (polyethyleneimine), following which folic acid was attached to the amino groups to permit targeting of certain cancer cell lines which express high levels of folate receptor.