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个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职：中国化学会创始会士、常务理事，中国化工学会会士
性别：男
毕业院校：大连理工大学
学位：博士
所在单位：化工学院
学科：应用化学. 精细化工. 化学生物学
办公地点：大连理工大学西部校区知顺楼F-202#
http://peng-group.dlut.edu.cn/
联系方式：大连理工大学西部校区知顺楼F-202 辽宁省大连市高新区凌工路2号，大连116024 课题组网址：http://peng-group.dlut.edu.cn/ E-mail: pengxj@dlut.edu.cn
电子邮箱：pengxj@dlut.edu.cn
A new PET fluorescent sensor for Zn2+
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论文类型：期刊论文
发表时间：2005-08-01
发表刊物：JOURNAL OF LUMINESCENCE
收录刊物：SCIE、EI、Scopus
卷号：114
期号：2
页面范围：125-130
ISSN号：0022-2313
关键字：zinc ion; 1,8-naphthalimide; fluorescent sensors; PET; fluorescent probe
摘要：A new Zn2+ fluorescent sensor NIDPA, with 1,8-naphthalimide as reporting group and di-2-picolylamine (DPA) as recognizing group, has been synthesized via simple steps. Based on photo-induced electron transfer (PET) mechanism, NIDPA has a five-fold fluorescent enhancement and 10nm absorption blue-shift under simulated physiological conditions corresponding to the binding of Zn2+. Apparent dissociation constant for Zn2+ (K-d) is 0.83 nM, and Ca2+, Mg2+, Fe2+, Ni2+ and Cr3+ have little influence on fluorescent enhancement. These results suggest that NIDPA can be used to quantitatively and selectively measure the concentration of Zn2+ around sub-nanomolar range. (c) 2005 Elsevier B.V. All rights reserved.