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个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职：Director, State Key laboratory of Fine Chemicals
其他任职：精细化工国家重点实验室主任、国务院学科评议组成员
性别：男
毕业院校：大连理工大学
学位：博士
所在单位：化工学院
学科：应用化学. 精细化工. 化学生物学
办公地点：大连理工大学精细化工国家重点实验室
西部校区化工实验楼F-202#
http://peng-group.dlut.edu.cn/
联系方式：大连理工大学精细化工国家重点实验室 西部校区化工实验楼F-202 辽宁省大连市高新区凌工路2号，大连116024 Tel: 0411-84986306; Fax: 0411-84986292；课题组网址：http://peng-group.dlut.edu.cn/
电子邮箱：pengxj@dlut.edu.cn
Syntheses, spectral properties and photo stabilities of novel water-soluble near-infrared cyanine dyes
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论文类型：期刊论文
发表时间：2004-11-01
发表刊物：JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
收录刊物：Scopus、SCIE
卷号：168
期号：1-2
页面范围：53-57
ISSN号：1010-6030
关键字：cyanine dyes; near-infrared dyes; photostability; biological assay; fluorescent dyes
摘要：To develop long wavelength cyanine dyes with good water solubility and high photostability for biological application, a series of heptamethine 5-sulfo-3H-indocyanine dyes were synthesized and characterized. The absorption and fluorescence spectra of the dyes in various solvents are presented, the maximum absorption and emission wavelengths ranging from 680 to 830 nm. The photostabilities are influenced by the different substitutes of the dyes: N-benzyl on the nitrogen atom at the 3H-indole ring provides better photostability than N-ethyl, the substitution of chloro group of chlorocyclohexenyl bridge in heptamethine chain with electron-donor group (such as 4-methoxylanilino) could greatly improve the photostability. In addition, the photofading is more rapid in water than in alcohol and the mechanisms are discussed. (C) 2004 Elsevier B.V. All rights reserved.