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个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职：Director, State Key laboratory of Fine Chemicals
其他任职：精细化工国家重点实验室主任、国务院学科评议组成员
性别：男
毕业院校：大连理工大学
学位：博士
所在单位：化工学院
学科：应用化学. 精细化工. 化学生物学
办公地点：大连理工大学精细化工国家重点实验室
西部校区化工实验楼F-202#
http://peng-group.dlut.edu.cn/
联系方式：大连理工大学精细化工国家重点实验室 西部校区化工实验楼F-202 辽宁省大连市高新区凌工路2号，大连116024 Tel: 0411-84986306; Fax: 0411-84986292；课题组网址：http://peng-group.dlut.edu.cn/
电子邮箱：pengxj@dlut.edu.cn
Syntheses and spectral properties of fluorescent trimethine sulfo-3H-indocyanine dyes
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论文类型：期刊论文
发表时间：2002-08-01
发表刊物：DYES AND PIGMENTS
收录刊物：Scopus、SCIE、EI
卷号：54
期号：2
页面范围：107-111
ISSN号：0143-7208
关键字：sulfo-3H-indocyanine; fluorescent dyes; biological label
摘要：Novel fluorescent sulfo-3H-indocyanine dyes containing at least one p-carboxybenzyl group on the nitrogen atoms in 3H-indocyanine rings were synthesized. Their lambda(abs) are in the range of 547-551 nm and lambda(em) 562-567 nm in water. When solvents change from water to ethanol or DMF, the lambda(abs) and lambda(em) of the dyes exhibit red shifts. Because of the presence of sulfonate groups and carboxyl groups, these dyes have good aqueous solubility. The p-carboxybenzyl group let the dyes have better photo-stability than commercial 5-carboxylpentynyl- containing dyes. The carboxyl groups can be converted into their N-hydroxylsuccinimidyl esters to label proteins, oligonucleotides or other bio-chemicals. (C) 2002 Elsevier Science Ltd. All rights reserved.