He Gaohong   

Professor
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates

Title : Director of R & D Center of Membrane Science and Technology

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Language:English

Paper Publications

Title of Paper:对肝硬化腹水进行净化并超滤浓缩的实验研究

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Date of Publication:2009-10-15

Journal:大连医科大学学报

Included Journals:Scopus、ISTIC

Volume:31

Issue:5

Page Number:513-515,518

ISSN No.:1671-7295

Key Words:CA/PEI亲和膜;中空纤维膜;内毒素;胆红素;浓缩

Abstract:[目的]净化和优化肝硬化腹水使其更有利于浓缩回输治疗.[方法]采用CA/PEI亲和膜去除腹水胆红素、内毒素,并采用聚砜中空纤维膜超滤浓缩腹水,用内毒素测定仪、生化自动分析仪和免疫分析仪测定过膜前后各项指标.[结果]CA/PEI亲和膜吸咐前后腹水中的胆红素、内毒素均明显下降(P<0.01);胆红素吸附前(51.77±11.76)μmol/L;吸附后(21.18±6.83)μmol/L; 内毒素吸附前(3.777±0.233) EU/mL, 吸附后(0.341±0.322) EU/mL.白蛋白、离子、免疫球蛋白均无明显变化(P>0.05).腹水超滤浓缩5.5~6.5倍,蛋白质浓缩4.7~6.5倍,免疫球蛋白浓缩3倍,但离子无变化.[结论]用CA/PEI亲和膜可去除胆红素、内毒素,用聚砜中空纤维膜超滤浓缩能使腹水得到净化和蛋白浓缩.

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